Perskvist Nasrin, Norlin Loreana, Dillner Joakim
1 Department of Pathology-Cytology, Karolinska Institute, Karolinska University Hospital , Stockholm Sweden .
Biopreserv Biobank. 2015 Apr;13(2):94-7. doi: 10.1089/bio.2014.0017. Epub 2015 Jan 19.
This article addresses the important issue of the standardization of the biobank process. It reports on i) the implementation of standard operating procedures for the processing of liquid-based cervical cells, ii) the standardization of storage conditions, and iii) the ultimate establishment of nationwide standardized biorepositories for cervical specimens. Given the differences in the infrastructure and healthcare systems of various county councils in Sweden, these efforts were designed to develop standardized methods of biobanking across the nation. The standardization of cervical sample processing and biobanking is an important and widely acknowledged issue. Efforts to address these concerns will facilitate better patient care and improve research based on retrospective and prospective collections of patient samples and cohorts. The successful nationalization of the Cervical Cytology Biobank in Sweden is based on three vital issues: i) the flexibility of the system to adapt to other regional systems, ii) the development of the system based on national collaboration between the university and the county councils, and iii) stable governmental financing by the provider, the Biobanking and Molecular Resource Infrastructure of Sweden (BBMRI.se). We will share our experiences with biorepository communities to promote understanding of and advances in opportunities to establish a nationalized biobank which covers the healthcare of the entire nation.
本文探讨了生物样本库流程标准化这一重要问题。报告内容包括：i）液基宫颈细胞处理标准操作程序的实施；ii）储存条件的标准化；iii）最终建立全国范围内标准化的宫颈标本生物样本库。鉴于瑞典各郡议会基础设施和医疗系统存在差异，这些努力旨在开发全国统一的生物样本库标准化方法。宫颈样本处理和生物样本库的标准化是一个重要且得到广泛认可的问题。解决这些问题的努力将有助于提供更好的患者护理，并改善基于患者样本和队列回顾性及前瞻性收集的研究。瑞典宫颈细胞学生物样本库的成功国有化基于三个关键问题：i）系统适应其他区域系统的灵活性；ii）基于大学与郡议会之间全国性合作的系统开发；iii）由瑞典生物样本库与分子资源基础设施（BBMRI.se）这一提供者提供稳定的政府资金支持。我们将与生物样本库社区分享我们的经验，以促进对建立覆盖全国医疗保健的国有化生物样本库的机会的理解和进展。
