Scheper Mark, de Vries Janneke, Beelen Anita, de Vos Rien, Nollet Frans, Engelbert Raoul
Amsterdam School of Health Professions, Education of Physiotherapy, Tafelbergweg 51, 1105BD, Amsterdam, The Netherlands.
Curr Rheumatol Rev. 2014;10(2):117-25. doi: 10.2174/1573397111666150120112925.
Generalized Joint Hypermobility (GJH) is regarded as the main diagnostic criterion for Hypermobility Syndrome and is assumed to be of importance for the development of musculoskeletal complaints and functional decline. However GJH is also highly prevalent amongst healthy individuals whereas its consequences for physical functioning are unclear. Therefore the objective of the study was to determine the association of GJH with physical functioning in healthy adolescents and young adults.
328 participants (mean age (sd): 20.2 (1.8), gender (male/female): 134/194) were included. In order to establish the effect of GJH, subjects with symptomatic forms of GJH were excluded, as were subjects with other conditions that could influence physical functioning. Age, gender, BMI, GJH, muscle strength and physical activity level (PAL) in METS were collected.
GJH was associated with reduced muscle strength for all muscle groups (p=<.05), controlled for age and BMI. Ranging from -0.7 to -1.0SD in females and -.3 to -1.3SD in males. GJH was found to be significantly associated with higher amounts of METS spent on cycling, ranging from +0.2 to +0.9SD in females (p=.002) and +0.3 to +0.9SD in males (p=.041), where lower amounts of METS spent on sports activities was observed, ranging from -0.4 to -1.2SD in females (p=.002) and -0.2 to -1.9SD in males (p=.004).
Individuals with GJH have reduced muscle strength and tend to avoid dynamic activities and prefer more stable activities, like cycling. This may indicate that individuals with GJH adapt their behaviour to prevent musculoskeletal complaints and functional decline.
全身关节过度活动（GJH）被视为过度活动综合征的主要诊断标准，并且被认为对肌肉骨骼疾病的发展和功能衰退具有重要意义。然而，GJH在健康个体中也非常普遍，而其对身体功能的影响尚不清楚。因此，本研究的目的是确定GJH与健康青少年和年轻人身体功能之间的关联。
纳入328名参与者（平均年龄（标准差）：20.2（1.8），性别（男/女）：134/194）。为了确定GJH的影响，排除了有症状形式的GJH受试者以及其他可能影响身体功能的疾病受试者。收集了年龄、性别、体重指数、GJH、肌肉力量和以代谢当量表示的身体活动水平（PAL）。
在控制年龄和体重指数的情况下，GJH与所有肌肉群的肌肉力量降低相关（p<0.05）。女性降低范围为-0.7至-1.0标准差，男性为-0.3至-1.3标准差。发现GJH与骑自行车时消耗的较高代谢当量显著相关，女性为+0.2至+0.9标准差（p=0.002），男性为+0.3至+0.9标准差（p=0.041），而在体育活动中消耗的代谢当量较低，女性为-0.4至-1.2标准差（p=0.002），男性为-0.2至-1.9标准差（p=0.004）。
患有GJH的个体肌肉力量降低，倾向于避免动态活动，更喜欢更稳定的活动，如骑自行车。这可能表明患有GJH的个体调整其行为以预防肌肉骨骼疾病和功能衰退。
