金纳米粒子包覆氧化锌纳米棒作为基质用于增强 L-乳酸传感。
Gold nanoparticles coated zinc oxide nanorods as the matrix for enhanced L-lactate sensing.
机构信息
State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.
State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.
出版信息
Colloids Surf B Biointerfaces. 2015 Feb 1;126:476-80. doi: 10.1016/j.colsurfb.2014.12.053. Epub 2015 Jan 7.
In this study, an enzymatic electrochemical biosensor for L-lactate detection was proposed. The device was developed based on gold nanoparticles (Au NPs) modified zinc oxide nanorods (ZnO NRs). The sensing performance of the device was examined by cyclic voltammetry and amperometry. Compared with pristine ZnO based biosensor, Au/ZnO based sensor exhibited higher sensitivity of 24.56 μA cm(-2) mM(-1), smaller K(M)(app) of 1.58 mM, lower detection limit of 6 μM and wider linear range of 10 μM-0.6 mM for L-lactate detection. The introduction of Au NPs enhances electro-catalytic ability and electron migration, which contributes to the improvement of the sensing performance. Hence, the results confirm the essential character of Au NPs in such semiconductor based electrochemical biosensing system.
在这项研究中，提出了一种用于检测 L-乳酸的酶电化学生物传感器。该装置是基于金纳米粒子（Au NPs）修饰的氧化锌纳米棒（ZnO NRs）开发的。通过循环伏安法和安培法对器件的传感性能进行了测试。与原始 ZnO 基生物传感器相比，Au/ZnO 基传感器表现出更高的灵敏度（24.56 μA cm(-2) mM(-1))，更小的表观米氏常数（1.58 mM），更低的检测限（6 μM）和更宽的线性范围（10 μM-0.6 mM）用于检测 L-乳酸。Au NPs 的引入增强了电催化能力和电子迁移率，这有助于提高传感性能。因此，结果证实了 Au NPs 在这种基于半导体的电化学生物传感系统中的重要作用。
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