Mai Hanh Hong, Janssens Ewald
Faculty of Physics, University of Science, Vietnam National University, 334 Nguyen Trai, Hanoi, 100000, Vietnam.
Quantum Solid-State Physics, Department of Physics and Astronomy, KU Leuven, Celestijnenlaan 200D, B-3001, Leuven, Belgium.
Mikrochim Acta. 2020 Sep 25;187(10):577. doi: 10.1007/s00604-020-04563-6.
ZnO nanorods (NRs) synthesized by a hydrothermal method and decorated with Au nanoparticles (NPs) were used for fluorescent non-enzymatic glucose detection. The detection is based on the photoluminescence (PL) quenching of ZnO NRs/Au NPs (at 382 nm under 325 nm excitation) exposed to glucose. The sensor exhibits a high sensitivity of (22 ± 2) % mM (defined as percentage change of the PL peak intensity per mM) and a limit of detection (LOD) as low as 0.01 mM, along with an excellent selectivity and a short response time (less than 5 s). In comparison with a fluorescent non-enzymatic ZnO nanostructure-based glucose sensor, the addition of Au NPs significantly enhances the sensitivity. This is attributed to the surface plasmon resonance, which increases not only the photoluminescence intensity but also the photo-oxidation property of the ZnO NRs. Thus, ZnO NRs/Au NPs can act as an efficient photocatalyst for glucose detection. Most importantly, the probe is applicable to glucose detection in human blood serum. The outstanding performance of the material and its cost-effectiveness allow for potential application in single-use, noninvasive glucose devices.Graphical abstract A sensitive non-enzymatic fluorescent glucose probe-based ZnO nanorod decorated with Au nanoparticles.
通过水热法合成并用金纳米颗粒（NPs）修饰的氧化锌纳米棒（NRs）用于荧光非酶葡萄糖检测。该检测基于暴露于葡萄糖的氧化锌纳米棒/金纳米颗粒（在325nm激发下于382nm处）的光致发光（PL）猝灭。该传感器具有（22±2）% mM的高灵敏度（定义为每mM的PL峰强度的百分比变化）和低至0.01 mM的检测限（LOD），以及出色的选择性和短响应时间（小于5秒）。与基于荧光非酶氧化锌纳米结构的葡萄糖传感器相比，金纳米颗粒的添加显著提高了灵敏度。这归因于表面等离子体共振，其不仅增加了光致发光强度，还增加了氧化锌纳米棒的光氧化性能。因此，氧化锌纳米棒/金纳米颗粒可作为葡萄糖检测的有效光催化剂。最重要的是，该探针适用于人血清中的葡萄糖检测。该材料的出色性能及其成本效益使其在一次性非侵入式葡萄糖检测设备中具有潜在应用价值。图形摘要：一种基于金纳米颗粒修饰的氧化锌纳米棒的灵敏非酶荧光葡萄糖探针。
