• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Ethical, legal and social implications of incorporating personalized medicine into healthcare.将个性化医疗纳入医疗保健的伦理、法律和社会影响。
Per Med. 2015;12(1):43-51. doi: 10.2217/pme.14.65.
2
Ethical, Legal, and Social Implications of Personalized Genomic Medicine Research: Current Literature and Suggestions for the Future.个性化基因组医学研究的伦理、法律和社会影响:当前文献及未来建议
Bioethics. 2016 Nov;30(9):698-705. doi: 10.1111/bioe.12285.
3
Genetic/genomic testing: defining the parameters for ethical, legal and social implications (ELSI).遗传/基因组检测:定义伦理、法律和社会影响(ELSI)的参数。
BMC Med Ethics. 2021 Nov 23;22(1):156. doi: 10.1186/s12910-021-00720-5.
4
REVISITING HEALTH INFORMATION TECHNOLOGY ETHICAL, LEGAL, and SOCIAL ISSUES and EVALUATION: TELEHEALTH/TELEMEDICINE and COVID-19.重新审视健康信息技术的伦理、法律和社会问题及评估:远程医疗/远程医学和 COVID-19。
Int J Med Inform. 2020 Nov;143:104239. doi: 10.1016/j.ijmedinf.2020.104239. Epub 2020 Jul 31.
5
SOCIO-ETHICAL ISSUES IN PERSONALIZED MEDICINE: A SYSTEMATIC REVIEW OF ENGLISH LANGUAGE HEALTH TECHNOLOGY ASSESSMENTS OF GENE EXPRESSION PROFILING TESTS FOR BREAST CANCER PROGNOSIS.个性化医疗中的社会伦理问题:对用于乳腺癌预后的基因表达谱检测的英文健康技术评估的系统评价
Int J Technol Assess Health Care. 2015 Jan;31(1-2):36-50. doi: 10.1017/S0266462315000082. Epub 2015 May 20.
6
Ethical, legal, and social implications (ELSI) of virtual agents and virtual reality in healthcare.医疗保健中虚拟代理和虚拟现实的伦理、法律和社会影响(ELSI)。
Soc Sci Med. 2024 Jan;340:116483. doi: 10.1016/j.socscimed.2023.116483. Epub 2023 Dec 1.
7
Perception of personalized medicine, pharmacogenomics, and genetic testing among undergraduates in Hong Kong.香港本科生对个性化医学、药物基因组学和基因检测的认知。
Hum Genomics. 2021 Aug 18;15(1):54. doi: 10.1186/s40246-021-00353-0.
8
Ethical, Legal, and Social Issues (ELSI) in Clinical Genetics Research.临床遗传学研究中的伦理、法律和社会问题 (ELSI)。
Methods Mol Biol. 2021;2249:65-82. doi: 10.1007/978-1-0716-1138-8_5.
9
Clinical genetic research 3: Genetics ELSI (Ethical, Legal, and Social Issues) research.临床遗传学研究3:遗传学中的伦理、法律和社会问题(ELSI)研究。
Methods Mol Biol. 2015;1281:369-82. doi: 10.1007/978-1-4939-2428-8_22.
10
Unraveling the Ethical, Legal, and Social Implications of Neurobiobanking and Stroke Genomic Research in Africa: A Study Protocol of the African Neurobiobank for Precision Stroke Medicine ELSI Project.剖析非洲神经生物样本库与中风基因组研究的伦理、法律和社会影响:非洲精准中风医学神经生物样本库ELSI项目研究方案
Int J Qual Methods. 2020 Jan-Dec;19. doi: 10.1177/1609406920923194. Epub 2020 Jun 23.

引用本文的文献

1
Building a Hand-Curated ceRNET for Endometrial Cancer, Striving for Clinical as Well as Medicolegal Soundness: A Systematic Review.构建子宫内膜癌人工筛选的ceRNET,追求临床及法医学合理性:一项系统评价
Noncoding RNA. 2025 Apr 30;11(3):34. doi: 10.3390/ncrna11030034.
2
Ethical and legal considerations in healthcare AI: innovation and policy for safe and fair use.医疗保健人工智能中的伦理和法律考量:安全公平使用的创新与政策
R Soc Open Sci. 2025 May 14;12(5):241873. doi: 10.1098/rsos.241873. eCollection 2025 May.
3
Distributional Cost-Effectiveness Analysis in Genomic Medicine: Considerations for Addressing Health Equity.基因组医学中的分布成本效益分析:解决健康公平问题的考量因素
Value Health. 2025 May 6. doi: 10.1016/j.jval.2025.04.2162.
4
A scoping review of the development of genetic counseling practices in Asia.亚洲遗传咨询实践发展的范围综述。
J Genet Couns. 2025 Jun;34(3):e70036. doi: 10.1002/jgc4.70036.
5
Revolutionizing Personalized Medicine: Synergy with Multi-Omics Data Generation, Main Hurdles, and Future Perspectives.变革个性化医疗:与多组学数据生成的协同作用、主要障碍及未来展望
Biomedicines. 2024 Nov 30;12(12):2750. doi: 10.3390/biomedicines12122750.
6
Precision Emergency Medicine: A Systematic Review.精准急诊医学:一项系统综述
Cureus. 2024 Dec 3;16(12):e75068. doi: 10.7759/cureus.75068. eCollection 2024 Dec.
7
Eleven Grand Challenges for Inflammatory Bowel Disease Genetics and Genomics.炎症性肠病遗传学和基因组学的十一项重大挑战。
Inflamm Bowel Dis. 2025 Jan 6;31(1):272-284. doi: 10.1093/ibd/izae269.
8
Knee Arthroscopy in the Era of Precision Medicine: A Comprehensive Review of Tailored Approaches and Emerging Technologies.精准医学时代的膝关节镜检查:定制方法与新兴技术的全面综述
Cureus. 2024 Oct 6;16(10):e70932. doi: 10.7759/cureus.70932. eCollection 2024 Oct.
9
Mitophagy and cGAS-STING crosstalk in neuroinflammation.神经炎症中的线粒体自噬与cGAS-STING相互作用
Acta Pharm Sin B. 2024 Aug;14(8):3327-3361. doi: 10.1016/j.apsb.2024.05.012. Epub 2024 May 13.
10
Navigating the Landscape of Digital Twins in Medicine: A Relational Bioethical Inquiry.探索医学数字孪生的全景:一项关系生物伦理探究。
Asian Bioeth Rev. 2024 Apr 23;16(3):471-481. doi: 10.1007/s41649-024-00280-x. eCollection 2024 Jul.

本文引用的文献

1
Autonomy and paternalism in health policy: currents in contemporary bioethics.卫生政策中的自主性与家长主义:当代生物伦理学思潮
J Law Med Ethics. 2014 Winter;42(4):590-4. doi: 10.1111/jlme.12178.
2
Socioeconomic inequalities in health after age 50: are health risk behaviors to blame?50 岁后健康的社会经济不平等:健康风险行为是否应该受到指责?
Soc Sci Med. 2014 Jan;101:52-60. doi: 10.1016/j.socscimed.2013.10.040. Epub 2013 Nov 16.
3
How could disclosing incidental information from whole-genome sequencing affect patient behavior?披露全基因组测序中的偶然信息会如何影响患者的行为?
Per Med. 2013 Jun;10(4). doi: 10.2217/pme.13.24.
4
Personalized medicine and genetic malpractice.个性化医疗与基因医疗事故
Genet Med. 2013 Dec;15(12):921-2. doi: 10.1038/gim.2013.142. Epub 2013 Sep 26.
5
Recommendations for returning genomic incidental findings? We need to talk!关于如何报告基因组偶然发现的建议?我们需要谈谈!
Genet Med. 2013 Nov;15(11):854-9. doi: 10.1038/gim.2013.113. Epub 2013 Aug 1.
6
ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.ACMG 临床外显子组和基因组测序中偶然发现报告的推荐标准。
Genet Med. 2013 Jul;15(7):565-74. doi: 10.1038/gim.2013.73. Epub 2013 Jun 20.
7
What's so meaningful about meaningful use?有意义使用的意义何在?
Hastings Cent Rep. 2013 Mar-Apr;43(2):15-7. doi: 10.1002/hast.154.
8
Personalized genomic medicine and the rhetoric of empowerment.个体化基因组医学与赋权话语。
Hastings Cent Rep. 2012 Sep-Oct;42(5):34-40. doi: 10.1002/hast.65.
9
Currents in contemporary bioethics. Access to sensitive information in segmented electronic health records.当代生物伦理学中的热点问题。分段电子健康记录中敏感信息的获取。
J Law Med Ethics. 2012 Summer;40(2):394-400. doi: 10.1111/j.1748-720X.2012.00673.x.
10
Personalized medicine and access to health care: potential for inequitable access?个性化医疗与医疗保健的可及性:潜在的不公平获取?
Eur J Hum Genet. 2013 Feb;21(2):143-7. doi: 10.1038/ejhg.2012.149. Epub 2012 Jul 11.

将个性化医疗纳入医疗保健的伦理、法律和社会影响。

Ethical, legal and social implications of incorporating personalized medicine into healthcare.

作者信息

Brothers Kyle B, Rothstein Mark A

机构信息

Kosair Charities Pediatric Clinical Research Unit, Department of Pediatrics, 231 East Chestnut Street, N-97, Louisville, KY 40202, USA ; Department of Pediatrics, University of Louisville School of Medicine, Louisville, KY, USA ; Institute for Bioethics, Health Policy & Law, University of Louisville School of Medicine, Louisville, KY, USA.

Institute for Bioethics, Health Policy & Law, University of Louisville School of Medicine, Louisville, KY, USA ; Department of Medicine, University of Louisville School of Medicine, Louisville, KY, USA.

出版信息

Per Med. 2015;12(1):43-51. doi: 10.2217/pme.14.65.

DOI:10.2217/pme.14.65
PMID:25601880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4296905/
Abstract

As research focused on personalized medicine has developed over the past decade, bioethics scholars have contemplated the ethical, legal and social implications of this type of research. In the next decade, there will be a need to broaden the focus of this work as personalized medicine moves into clinical settings. We consider two broad issues that will grow in importance and urgency. First, we analyze the consequences of the significant increase in health information that will be brought about by personalized medicine. Second, we raise concerns about the potential of personalized medicine to exacerbate existing disparities in healthcare.

摘要

在过去十年中,随着聚焦于个性化医疗的研究不断发展,生物伦理学者一直在思考这类研究的伦理、法律和社会影响。在接下来的十年里,随着个性化医疗进入临床环境,有必要拓宽这项工作的重点。我们考虑两个将变得更加重要和紧迫的广泛问题。首先,我们分析个性化医疗将带来的健康信息大幅增加的后果。其次,我们对个性化医疗加剧现有医疗保健差距的可能性表示担忧。