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[原发性胃弥漫性大B细胞淋巴瘤所致胃穿孔]

[Gastric perforation caused by primary gastric diffuse large B cell lymphoma].

作者信息

Kim Ju Seok, Rou Woo Sun, Ahn Byung Moo, Moon Hee Seok, Kang Sun Hyung, Sung Jae Kyu, Jeong Hyun Yong, Song Kyu-Sang

机构信息

Departments of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.

Departments of Pathology, Chungnam National University School of Medicine, Daejeon, Korea.

出版信息

Korean J Gastroenterol. 2015 Jan;65(1):43-7. doi: 10.4166/kjg.2015.65.1.43.

Abstract

Spontaneous gastric perforation is a rare complication of gastric lymphoma that is potentially life threatening since it can progress to sepsis and multi-organ failure. Morbidity also increases due to prolonged hospitalization and delay in initiating chemotherapy. Therefore prompt diagnosis and appropriate treatment is critical to improve prognosis. A 64-year-old man presented to the emergency department with severe abdominal pain. Chest X-ray showed free air below the right diaphragm. Abdominal CT scan also demonstrated free air in the peritoneal cavity with large wall defect in the lesser curvature of gastric lower body. Therefore, the patient underwent emergency operation and primary closure was done. Pathologic specimen obtained during surgery was compatible to diffuse large B cell lymphoma. Fifteen days after primary closure, the patient received subtotal gastrectomy and chemotherapy was initiated after recovery. Patient is currently being followed-up at outpatient department without any particular complications. Herein, we report a rare case of gastric lymphoma that initially presented as peritonitis because of spontaneous gastric perforation.

摘要

自发性胃穿孔是胃淋巴瘤的一种罕见并发症,具有潜在的生命威胁,因为它可进展为败血症和多器官功能衰竭。由于住院时间延长和化疗启动延迟,发病率也会增加。因此,及时诊断和适当治疗对于改善预后至关重要。一名64岁男性因严重腹痛就诊于急诊科。胸部X线显示右膈下有游离气体。腹部CT扫描也显示腹腔内有游离气体,胃体下部小弯侧有大的壁缺损。因此,患者接受了急诊手术并进行了一期缝合。手术中获取的病理标本符合弥漫性大B细胞淋巴瘤。一期缝合15天后,患者接受了胃次全切除术,并在康复后开始化疗。患者目前在门诊随访,无任何特殊并发症。在此,我们报告一例罕见的胃淋巴瘤病例,该病例最初表现为自发性胃穿孔所致的腹膜炎。

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