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伴有狼疮抗凝物的自限性复发性大疱性过敏性紫癜

Self-limiting recurrent bullous Henoch-Schonlein purpura with lupus anticoagulant.

作者信息

Gration Betty, Osakwe Edwin

机构信息

Medical Sciences Department, Oxford University, Oxford, UK.

Department of Paediatrics, Oxford University Hospitals NHS Trust, Oxford, UK.

出版信息

BMJ Case Rep. 2015 Jan 20;2015:bcr2014205436. doi: 10.1136/bcr-2014-205436.

Abstract

Henoch-Schonlein purpura (HSP) is the most common acute systemic vasculitis of childhood with an incidence of approximately 1:10,000. It commonly presents with skin, gastrointestinal tract, joints and renal system signs and symptoms. We present a case of recurrent self-limiting HSP with lupus anticoagulant presenting with haemorrhagic bullous skin lesions and scrotal swelling. The initial presentation resolved within 4 weeks but over the next 6 months, a few self-limiting but milder skin lesions occurred. Some institutions have advocated the use of steroids in these cases but our case showed that the use of steroids may not be required. This atypical presentation of HSP led to unnecessary investigations that this case report aims to prevent in the future by raising its awareness.

摘要

过敏性紫癜(HSP)是儿童期最常见的急性全身性血管炎,发病率约为1:10000。其通常表现为皮肤、胃肠道、关节和肾脏系统的体征和症状。我们报告一例复发性自限性HSP合并狼疮抗凝物,表现为出血性大疱性皮肤病变和阴囊肿胀。初始表现4周内消退,但在接下来的6个月里,出现了一些自限性但较轻的皮肤病变。一些机构主张在这些病例中使用类固醇,但我们的病例表明可能不需要使用类固醇。HSP的这种非典型表现导致了不必要的检查,本病例报告旨在通过提高认识来防止未来出现此类情况。

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