过敏性紫癜后的狼疮抗凝物与血栓形成

Lupus anticoagulant and thrombosis following Henoch-Schonlein purpura.

作者信息

Abend Nicholas S, Licht Daniel J, Spencer Charles H

机构信息

Division of Neurology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

出版信息

Pediatr Neurol. 2007 May;36(5):345-7. doi: 10.1016/j.pediatrneurol.2007.01.005.

DOI:10.1016/j.pediatrneurol.2007.01.005

PMID:17509470

Abstract

A male adolescent developed a sinovenous thrombosis 4 weeks following a Henoch-Schonlein purpura episode. A hypercoagulation evaluation revealed a positive lupus anticoagulant. This suggests an association between Henoch-Schonlein purpura and antiphospholipid antibody syndrome and is the first report of sinovenous thrombosis after Henoch-Schonlein purpura that was likely due to elevated antiphospholipids. Children who develop Henoch-Schonlein purpura with neurologic features including headache should be evaluated for sinovenous thrombosis and a hypercoagulable state.

摘要

一名男性青少年在过敏性紫癜发作4周后发生了静脉窦血栓形成。高凝状态评估显示狼疮抗凝物阳性。这表明过敏性紫癜与抗磷脂抗体综合征之间存在关联，并且是首例可能因抗磷脂升高导致的过敏性紫癜后静脉窦血栓形成的报告。发生过敏性紫癜且伴有包括头痛在内的神经系统特征的儿童，应评估是否存在静脉窦血栓形成和高凝状态。