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完全腹腔镜下微波消融联合门静脉结扎分期肝切除术:一种新型的微创两阶段肝切除术

Totally Laparoscopic Microwave Ablation and Portal Vein Ligation for Staged Hepatectomy : A New Minimally Invasive Two-Stage Hepatectomy.

作者信息

Cillo Umberto, Gringeri Enrico, Feltracco Paolo, Bassi Domenico, D'Amico Francesco E, Polacco Marina, Boetto Riccardo

机构信息

Hepatobiliary Surgery and Liver Transplant Unit, Azienda Università di Padova, University of Padova, Padua, Italy.

出版信息

Ann Surg Oncol. 2015 Aug;22(8):2787-8. doi: 10.1245/s10434-014-4353-7. Epub 2015 Jan 21.

Abstract

BACKGROUND

Laparoscopic microwave ablation and portal vein ligation for staged hepatectomy (LAPS) is a new technique with a first laparoscopic step available in cases of unresectable right liver masses and inadequate future liver remnant (FLR).

METHODS

In Step 1, laparoscopic right portal vein occlusion is performed with microwave ablation on the future transection plane and in the FLR. Step 2 consists of a totally laparoscopic right trisectionectomy.

RESULTS

Duration of the Step 1 operation was 170 min, without the need for blood transfusions and intensive care unit admission. The postoperative liver volumetric computed tomography scan was performed on postoperative day 9 and revealed a satisfactory left hepatic hypertrophy (FLR 666 cm(3); FLR to body weight ratio 0.96; FLR increase 90.4 %; daily FLR hypertrophy 35 cm(3)/day). Duration of the Step 2 operation was 630 min (liver transection time 240 min). Blood loss was 700 cc, with no need for transfusion. The specimen was extracted through a 10-cm Pfannenstiel incision, and pathology revealed a tumor-free resection margin (R0). The patient was discharged on postoperative day 7 without complications (total hospital stay for Step 1 + Step 2: 10 days).

CONCLUSIONS

Totally LAPS is a technically feasible and safe procedure. It could provide benefit in selected patients with primarily non-resectable liver cancer, making extreme liver surgery easy and safe in well-selected patients.

摘要

背景

腹腔镜微波消融联合门静脉结扎分期肝切除术(LAPS)是一种新技术,对于不可切除的右肝肿块和未来肝残余量(FLR)不足的病例,第一步可采用腹腔镜手术。

方法

第一步,在未来的肝切除平面和FLR区域进行腹腔镜下右门静脉闭塞并微波消融。第二步为完全腹腔镜下右三叶切除术。

结果

第一步手术持续时间为170分钟,无需输血及入住重症监护病房。术后第9天行肝脏容积计算机断层扫描,显示左肝肥大情况良好(FLR为666 cm³;FLR与体重比为0.96;FLR增加90.4%;每日FLR肥大35 cm³/天)。第二步手术持续时间为630分钟(肝切除时间240分钟)。失血700 cc,无需输血。标本通过10 cm的耻骨上横切口取出,病理显示切缘无肿瘤(R0)。患者术后第7天出院,无并发症(第一步 + 第二步总住院时间:10天)。

结论

完全LAPS是一种技术上可行且安全的手术。对于部分原发性不可切除肝癌患者可能有益,能使精心挑选的患者进行极限肝脏手术变得轻松且安全。

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