Xu Hong-Wei, Li Hong-Yu, Liu Fei, Wei Yong-Gang, Li Bo
Department of Liver Surgery, Center of Liver Transplantation Department of Pancreatic Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.
Medicine (Baltimore). 2017 Mar;96(11):e6368. doi: 10.1097/MD.0000000000006368.
Resection of the liver is often limited to the insufficient future liver remnant (FLR). To address this problem, the modification surgical technique "associating liver tourniquet and portal vein occlusion for staged hepatectomy" (ALTPS) was developed and led to quick hypertrophy in a short interval. In some colorectal cancer patients with multiple and bilobar metastases, the resection of the primary is often protracted immensely to the unpredictable postoperative complications for whom is to be treated with a liver-first approach. To overcome this problem, a simultaneous resection of the primary tumor and totally laparoscopic ALTPS for bilateral liver metastases of the primary colon cancer were performed.
A 63-year-old female patient with left colon cancer and synchronous bilateral colorectal liver metastases underwent a totally laparoscopic ALTPS and simultaneous left hemicolectomy because of the small FLR. The operative times were 460 minutes for the first stage and 240 minutes for the second stage without the need for blood transfusions. The recoveries after the first and the second operations were uneventful, and the patient was discharged on postoperative day 11 of the second stage operation.
Our case shows the totally laparoscopic ALTPS and simultaneous left hemicolectomy at step 1 for bilobar liver metastases of the primary colon cancer with no severe postoperative complications. If a resection of the primary tumor does not compromise the split procedure, the combination of pure laparoscopic ALTPS and primary resection is feasible and safe.
肝切除术常因未来肝剩余量(FLR)不足而受限。为解决这一问题,开发了改良手术技术“联合肝门阻断和门静脉结扎分期肝切除术”(ALTPS),可在短时间内实现快速肥大。在一些患有多发和双侧转移的结直肠癌患者中,原发灶的切除往往因不可预测的术后并发症而大幅延长,这些患者需采用肝优先方法治疗。为克服这一问题,对原发性结肠癌双侧肝转移患者进行了原发肿瘤的同期切除及完全腹腔镜下ALTPS。
一名63岁女性患者,患有左结肠癌并同时发生双侧结直肠癌肝转移,因FLR较小,接受了完全腹腔镜下ALTPS及同期左半结肠切除术。第一阶段手术时间为460分钟,第二阶段为240分钟,无需输血。第一阶段和第二阶段手术后恢复顺利,患者在第二阶段手术后第11天出院。
我们的病例显示,对于原发性结肠癌双侧肝转移患者,在第一步进行完全腹腔镜下ALTPS及同期左半结肠切除术,术后无严重并发症。如果原发肿瘤的切除不影响分期手术,单纯腹腔镜下ALTPS与原发灶切除相结合是可行且安全的。