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里约热内卢一个棚户区人群轮状病毒感染的血清学调查。

A serological investigation of rotavirus infections in a shanty town population in Rio de Janeiro.

作者信息

Azeredo R S, Leite J P, Pereira H G, Vidal M N, Sutmoller F, Maurice Y, Schatzmayr H G

出版信息

Rev Inst Med Trop Sao Paulo. 1989 Jul-Aug;31(4):262-6. doi: 10.1590/s0036-46651989000400009.

DOI:10.1590/s0036-46651989000400009
PMID:2560587
Abstract

The presence of antibodies against rotavirus was investigated by enzyme immunosorbent assay (ELISA) in two distinct groups of children living in a shanty town in Rio de Janeiro. One hundred and thirty six plasma samples were randomly collected from children of 0 to 33 months (first group) and 255 serum samples were collected from other 85 children at ages of 2, 6 and 9 months (second group). A high percentage of antibodies were found in the newborn children and this rate decreased progressively until the age of 11 months, after which it increased again. At the age of 7 months, geometric mean antibody titers increased indicating that infection had occurred.

摘要

通过酶联免疫吸附测定(ELISA)对居住在里约热内卢一个棚户区的两组不同儿童进行了抗轮状病毒抗体检测。从0至33个月大的儿童中随机采集了136份血浆样本(第一组),并从另外85名2、6和9个月大的儿童中采集了255份血清样本(第二组)。在新生儿中发现了高比例的抗体,该比例在11个月龄之前逐渐下降,之后又再次上升。在7个月龄时,几何平均抗体滴度升高,表明已发生感染。

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