韩国药用植物中黄曲霉毒素的污染发生率及污染水平。
Incidence and level of aflatoxins contamination in medicinal plants in Korea.
作者信息
Lee Sung Deuk, Yu In Sil, Jung Kweon, Kim Yeon Sun
机构信息
Seoul Metropolitan Government Research Institute of Public Health and Environment, Gwacheon 427-070, Korea.
Department of Public Health, Graduate School, Dankook University, Cheonan 330-714, Korea.
出版信息
Mycobiology. 2014 Dec;42(4):339-45. doi: 10.5941/MYCO.2014.42.4.339. Epub 2014 Dec 31.
During 20112013, a total of 729 samples for 19 types of medicinal plant were collected from Seoulyekryungsi in Seoul, Korea, and investigated for the presence of aflatoxins. The samples were analyzed using immunoaffinity column cleanup and high-performance liquid chromatography coupled to a fluorescence detector after post-column derivatization. Aflatoxins were found in 124 out of the 729 analyzed samples: 65 containing aflatoxin B1 (AFB1), 24 with aflatoxin B2 (AFB2), 15 with aflatoxin G1 (AFG1), and 20 samples with aflatoxin G2 (AFG2). The ranges for positive samples were 0.1404.7 µg/kg for AFB1, 0.110.0 µg/kg for AFB2, 0.1635.3 µg/kg for AFG1, 0.1182.5 µg/kg for AFG2, and 0.11,043.9 µg/kg for total aflatoxins. Most of the medicinal plant samples (721, 98.9%) were below legal limits, but 8 samples exceeded the legal limits of 10 and 15 µg/kg established by the Korean standard for AFB1 and total aflatoxins (the sum of AFB1, AFB2, AFG1 and AFG2), respectively.
2011年至2013年期间，从韩国首尔的首尔药令市共采集了19种药用植物的729个样本，检测其中黄曲霉毒素的存在情况。样本经免疫亲和柱净化后，采用柱后衍生化的高效液相色谱-荧光检测法进行分析。在729个分析样本中，有124个检测出黄曲霉毒素：65个含有黄曲霉毒素B1（AFB1），24个含有黄曲霉毒素B2（AFB2），15个含有黄曲霉毒素G1（AFG1），20个含有黄曲霉毒素G2（AFG2）。阳性样本中，AFB1的含量范围为0.1至404.7微克/千克，AFB2为0.1至10.0微克/千克，AFG1为0.1至635.3微克/千克，AFG2为0.1至182.5微克/千克，总黄曲霉毒素为0.1至1043.9微克/千克。大多数药用植物样本（721个，占98.9%）低于法定限量，但有8个样本分别超过了韩国标准规定的AFB1和总黄曲霉毒素（AFB1、AFB2、AFG1和AFG2之和）10微克/千克和15微克/千克的法定限量。
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