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LAMMER激酶在构巢曲霉营养生长期间细胞壁生物合成中的作用

Role of LAMMER Kinase in Cell Wall Biogenesis during Vegetative Growth of Aspergillus nidulans.

作者信息

Choi Yu Kyung, Kang Eun-Hye, Park Hee-Moon

机构信息

Department of Microbiology and Molecular Biology, College of Bioscience and Biotechnology, Chungnam National University, Daejeon 035-764, Korea.

出版信息

Mycobiology. 2014 Dec;42(4):422-6. doi: 10.5941/MYCO.2014.42.4.422. Epub 2014 Dec 31.

DOI:10.5941/MYCO.2014.42.4.422
PMID:25606019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4298851/
Abstract

Depending on the acquisition of developmental competence, the expression of genes for β-1,3-glucan synthase and chitin synthase was affected in different ways by Aspergillus nidulans LAMMER kinase. LAMMER kinase deletion, ΔlkhA, led to decrease in β-1,3-glucan, but increase in chitin content. The ΔlkhA strain was also resistant to nikkomycin Z.

摘要

根据发育能力的获得情况，构巢曲霉LAMMER激酶以不同方式影响β-1,3-葡聚糖合酶和几丁质合酶基因的表达。LAMMER激酶缺失（ΔlkhA）导致β-1,3-葡聚糖减少，但几丁质含量增加。ΔlkhA菌株对多氧霉素Z也具有抗性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8acf/4298851/dd7d062b4624/mb-42-422-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8acf/4298851/4b0e49e04cc9/mb-42-422-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8acf/4298851/dd7d062b4624/mb-42-422-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8acf/4298851/4b0e49e04cc9/mb-42-422-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8acf/4298851/dd7d062b4624/mb-42-422-g002.jpg

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LAMMER Kinase LkhA plays multiple roles in the vegetative growth and asexual and sexual development of Aspergillus nidulans.LAMMER 激酶 LkhA 在构巢曲霉的营养生长、无性和有性发育中发挥多种作用。
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Int J Mol Sci. 2022 Jul 22;23(15):8104. doi: 10.3390/ijms23158104.
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