Howell Lisa A, Brockman Tabetha A, Sinicrope Pamela S, Patten Christi A, Decker Paul A, Ehlers Shawna L, Lindor Noralane M, Nigon Sandra K, Petersen Gloria M
Department of Psychology and Psychiatry, 200 First St. SW, Mayo Clinic Rochester, MN 55905, USA.
Behavioral Health Research Program, Mayo Clinic Rochester, 200 First St. SW, Rochester, MN 55905, USA.
J Behav Health. 2013;2(4):279-290. doi: 10.5455/jbh.20130921013627.
Cancer is a shared family experience, and thus the purpose of this study was to assess receptivity and preferences for cancer risk reduction programs among at-risk family members with two or more relatives affected with colorectal cancer (CRC).
The sample comprised 401 at-risk family members with two or more relatives affected with CRC from the Colon Cancer Family Registry. In March 2009, respondents completed a mailed survey assessing receptivity and preferences for participating in cancer risk reduction programs and evaluated their relationship to demographic, medical, and psychosocial variables. Multivariable generalized estimating equation approaches were used to model preferences.
Overall, 81% of respondents were receptive to a lifestyle cancer risk reduction program; of these, about half (54%) preferred to participate with their family. Program preferences included: weight management (36%) and nutrition (31%); delivered through the internet (41%) or mail (39%). In a multivariate model, a greater level of concern about cancer (p<0.001), female gender (p=0.002), and higher education (p=0.016) were significantly correlated with willingness to participate in lifestyle programs.
Family members of those with CRC are receptive to cancer risk reduction programs that focus on weight management and nutrition delivered via the internet or mail. Future research is needed to determine how best to incorporate a family-based approach that addresses the cancer experience when designing lifestyle intervention programs.
癌症是一种会影响整个家庭的疾病，因此本研究的目的是评估有两名或更多亲属患结直肠癌（CRC）的高危家庭成员对癌症风险降低项目的接受程度和偏好。
样本包括来自结肠癌家族登记处的401名有两名或更多亲属患CRC的高危家庭成员。2009年3月，受访者完成了一项邮寄调查，评估参与癌症风险降低项目的接受程度和偏好，并评估了这些因素与人口统计学、医学和心理社会变量之间的关系。采用多变量广义估计方程方法对偏好进行建模。
总体而言，81%的受访者接受生活方式癌症风险降低项目；其中，约一半（54%）的人更愿意与家人一起参与。项目偏好包括：体重管理（36%）和营养（31%）；通过互联网（41%）或邮件（39%）提供。在多变量模型中，对癌症的更高关注度（p<0.001）、女性性别（p=0.002）和高等教育程度（p=0.016）与参与生活方式项目的意愿显著相关。
CRC患者的家庭成员接受以体重管理和营养为重点、通过互联网或邮件提供的癌症风险降低项目。未来需要进行研究，以确定在设计生活方式干预项目时，如何最好地纳入一种基于家庭的方法来应对癌症经历。
