Howell Lisa A, Sinicrope Pamela S, Brockman Tabetha A, Patten Christi A, Decker Paul A, Ehlers Shawna L, Nadeau Ashley, Rabe Kari G, Breitkopf Carmen Radecki, Petersen Gloria M
Department of Psychology and Psychiatry, Mayo Clinic Rochester, Rochester, MN, USA.
Behavioral Health Research Program, Mayo Clinic Rochester, Rochester, MN, USA.
Hered Cancer Clin Pract. 2013 May 31;11(1):3. doi: 10.1186/1897-4287-11-3.
Cancer is a shared family experience that might provide an opportunity for lifestyle change among at-risk family members. The purpose of this study was to assess receptivity and preferences for cancer risk reduction programs among at-risk family members with two or more relatives affected with pancreas cancer.
We surveyed 401 at-risk family members in an existing pancreatic cancer family registry. Participants completed a mailed survey which examined demographic, medical, and psychosocial correlates of willingness to participate in lifestyle cancer risk reduction programs. Multivariable generalized estimating equation approaches were used to model preferences.
Overall, 85% (n = 342) of at-risk family members were receptive to lifestyle cancer risk reduction programs. Participant preferred programs focused on nutrition (36%, n = 116) and weight management (33%, n = 108), with Web/Internet (46%, n = 157) being the most preferred delivery channel. Most respondents preferred to participate in programs with their family or friends (74%, n = 182), rather than alone (25%, n = 85). In multivariable analysis, younger age (p = 0.008) and higher perceived likelihood of developing cancer (p = 0.03) were associated with willingness to participate in lifestyle programs.
Family members of those with pancreatic cancer are receptive to cancer risk reduction programs focusing on nutrition and weight management delivered via the internet. Further research is indicated to determine how to best incorporate a family-based approach when designing lifestyle intervention programs.
癌症是一种家庭共同经历，可能为高危家庭成员提供改变生活方式的契机。本研究旨在评估有两名或更多亲属患胰腺癌的高危家庭成员对癌症风险降低项目的接受度和偏好。
我们对一个现有的胰腺癌家族登记处中的401名高危家庭成员进行了调查。参与者完成了一份邮寄调查问卷，该问卷调查了参与生活方式癌症风险降低项目意愿的人口统计学、医学和社会心理相关因素。采用多变量广义估计方程方法对偏好进行建模。
总体而言，85%（n = 342）的高危家庭成员接受生活方式癌症风险降低项目。参与者更喜欢侧重于营养（36%，n = 116）和体重管理（33%，n = 108）的项目，其中网络/互联网（46%，n = 157）是最受欢迎的传播渠道。大多数受访者更喜欢与家人或朋友一起参加项目（74%，n = 182），而不是独自参加（25%，n = 85）。在多变量分析中，年龄较小（p = 0.008）和患癌感知可能性较高（p = 0.03）与参与生活方式项目的意愿相关。
胰腺癌患者的家庭成员接受通过互联网提供的侧重于营养和体重管理的癌症风险降低项目。需要进一步研究以确定在设计生活方式干预项目时如何最好地纳入基于家庭的方法。
