Ronga Mario, Angeretti Gloria, Ferraro Sergio, DE Falco Giovanni, Genovese Eugenio A, Cherubino Paolo
Orthopaedics and Traumatology, Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Varese, Italy.
Radiology Unit, Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy.
Joints. 2014 Aug 1;2(3):137-40. doi: 10.11138/jts/2014.2.3.137. eCollection 2014 Jul-Sep.
Magnetic resonance imaging (MRI) is the gold standard method for non-invasive assessment of joint cartilage, providing information on the structure, morphology and molecular composition of this tissue. There are certain minimum requirements for a MRI study of cartilage tissue: machines with a high magnetic field (> 1.5 Tesla); the use of surface coils; and the use of T2-weighted, proton density-weighted fast-spin echo (T2 FSE-DP) and 3D fat-suppressed T1-weighted gradient echo (3D-FS T1W GRE) sequences. For better contrast between the different joint structures, MR arthography is a method that can highlight minimal fibrillation or fractures of the articular surface and allow evaluation of the integrity of the native cartilage-repair tissue interface. To assess the biochemical composition of cartilage and cartilage repair tissue, various techniques have been proposed for studying proteoglycans [dGEMRIC, T1rho mapping, sodium (23Na) imaging MRI, etc.], collagen, and water distribution [T2 mapping, "magnetisation transfer contrast", diffusion-weighted imaging (DWI), and so on]. Several MRI classifications have been proposed for evaluating the processes of joint degeneration (WORMS, BLOKS, ICRS) and post-surgical maturation of repair tissue (MOCART, 3D MOCART). In the future, isotropic 3D sequences set to improve image quality and facilitate the diagnosis of disorders of articular structures adjacent to cartilage.
磁共振成像(MRI)是用于关节软骨无创评估的金标准方法,可提供有关该组织的结构、形态和分子组成的信息。对软骨组织进行MRI研究有某些最低要求:具有高磁场(>1.5特斯拉)的机器;使用表面线圈;以及使用T2加权、质子密度加权快速自旋回波(T2 FSE-DP)和三维脂肪抑制T1加权梯度回波(3D-FS T1W GRE)序列。为了在不同关节结构之间获得更好的对比度,磁共振关节造影是一种可以突出关节表面微小纤维颤动或骨折并评估天然软骨-修复组织界面完整性的方法。为了评估软骨和软骨修复组织的生化组成,已经提出了各种技术来研究蛋白聚糖[dGEMRIC、T1rho成像、钠(23Na)成像MRI等]、胶原蛋白和水分布[T2成像、“磁化传递对比”、扩散加权成像(DWI)等]。已经提出了几种MRI分类方法来评估关节退变过程(WORMS、BLOKS、ICRS)和修复组织的术后成熟情况(MOCART、3D MOCART)。未来,各向同性三维序列将提高图像质量并有助于诊断与软骨相邻的关节结构疾病。