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Measurement of AKI biomarkers in the ICU: still striving for appropriate clinical indications.

作者信息

Prowle John R

机构信息

Adult Critical Care Unit, The Royal London Hospital, Barts Health NHS Trust, Whitechapel Road, London, E1 1BB, UK,

出版信息

Intensive Care Med. 2015 Mar;41(3):541-3. doi: 10.1007/s00134-015-3662-z. Epub 2015 Jan 22.

DOI:10.1007/s00134-015-3662-z
PMID:25608925
Abstract
摘要

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Measurement of AKI biomarkers in the ICU: still striving for appropriate clinical indications.重症监护病房中急性肾损伤生物标志物的测量：仍在为合适的临床指征而努力。
Intensive Care Med. 2015 Mar;41(3):541-3. doi: 10.1007/s00134-015-3662-z. Epub 2015 Jan 22.
2
Failure of renal biomarkers to predict worsening renal function in high-risk patients presenting with oliguria.在伴有少尿的高危患者中，肾生物标志物预测肾功能恶化的失败。
Intensive Care Med. 2015 Jan;41(1):68-76. doi: 10.1007/s00134-014-3566-3. Epub 2014 Dec 3.
3
Oliguria is an early predictor of higher mortality in critically ill patients.少尿是危重症患者死亡率升高的早期预测指标。
Kidney Int. 2011 Oct;80(7):760-7. doi: 10.1038/ki.2011.150. Epub 2011 Jun 29.
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Association of oliguria with the development of acute kidney injury in the critically ill.少尿与危重症患者急性肾损伤的发生有关。
Kidney Int. 2016 Jan;89(1):200-8. doi: 10.1016/j.kint.2015.12.007. Epub 2016 Jan 4.
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Increased urinary neutrophil gelatinase-associated lipocalin in very-low-birth-weight infants with oliguria and normal serum creatinine.少尿且血清肌酐正常的极低出生体重儿尿中性粒细胞明胶酶相关脂质运载蛋白增加。
Pediatr Nephrol. 2017 Jun;32(6):1059-1065. doi: 10.1007/s00467-016-3572-5. Epub 2017 Jan 12.
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Oliguria without serum creatinine increase after living donor liver transplantation is associated with adverse post-operative outcomes.活体供肝移植后无血清肌酐升高的少尿与术后不良结局相关。
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Defining oliguria during cardiopulmonary bypass and its relationship with cardiac surgery-associated acute kidney injury.定义体外循环期间的少尿及其与心脏手术相关的急性肾损伤的关系。
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Clinical Approach to Advanced Renal Function Testing in Dogs and Cats.犬猫高级肾功能检测的临床方法
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Protective role of antithrombin III in suppressing acute responses in a rat model of renal ischemia-reperfusion injury.抗凝血酶 III 在抑制肾缺血再灌注损伤大鼠模型急性反应中的保护作用。
Mol Cell Biochem. 2022 Feb;477(2):627-634. doi: 10.1007/s11010-021-04322-y. Epub 2022 Jan 5.
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A novel risk-predicted nomogram for sepsis associated-acute kidney injury among critically ill patients.一种新的预测危重病患者脓毒症相关急性肾损伤风险的列线图。
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Clinical prediction models for acute kidney injury.

本文引用的文献

1
Failure of renal biomarkers to predict worsening renal function in high-risk patients presenting with oliguria.在伴有少尿的高危患者中，肾生物标志物预测肾功能恶化的失败。
Intensive Care Med. 2015 Jan;41(1):68-76. doi: 10.1007/s00134-014-3566-3. Epub 2014 Dec 3.
2
Predictive value of NGAL for use of renal replacement therapy in patients with severe sepsis.中性粒细胞明胶酶相关脂质运载蛋白（NGAL）对严重脓毒症患者肾脏替代治疗应用的预测价值
Acta Anaesthesiol Scand. 2015 Jan;59(1):25-34. doi: 10.1111/aas.12427. Epub 2014 Nov 2.
3
Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication.
临床急性肾损伤预测模型。
Rev Bras Ter Intensiva. 2020 Mar;32(1):123-132. doi: 10.5935/0103-507x.20200018. Epub 2020 May 8.
4
High-sensitivity C-reactive protein as a predictive factor of acute kidney injury following aneurysmal subarachnoid hemorrhage: a prospective observational study.高敏 C 反应蛋白作为预测动脉瘤性蛛网膜下腔出血后急性肾损伤的指标：一项前瞻性观察研究。
Acta Neurochir (Wien). 2019 Sep;161(9):1783-1791. doi: 10.1007/s00701-019-04006-z. Epub 2019 Jul 17.
5
Urine -2-Microglobulin, Osteopontin, and Trefoil Factor 3 May Early Predict Acute Kidney Injury and Outcome after Cardiac Arrest.尿β2-微球蛋白、骨桥蛋白和三叶因子3可能早期预测心脏骤停后的急性肾损伤及预后。
Crit Care Res Pract. 2019 May 7;2019:4384796. doi: 10.1155/2019/4384796. eCollection 2019.
6
Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients.轻度至中度蛋白尿是重症监护病房患者急性肾损伤和死亡的先兆。
Turk J Med Sci. 2019 Apr 18;49(2):543-550. doi: 10.3906/sag-1802-183.
7
Paving the way for precision medicine v2.0 in intensive care by profiling necroinflammation in biofluids.通过在生物流体中描绘坏死性炎症，为重症监护的精准医学 2.0 铺平道路。
Cell Death Differ. 2019 Jan;26(1):83-98. doi: 10.1038/s41418-018-0196-2. Epub 2018 Sep 10.
8
AKI biomarkers are poor discriminants for subsequent need for renal replacement therapy, but do not disqualify them yet.急性肾损伤生物标志物对于预测后续肾脏替代治疗需求的能力欠佳，但尚未使其失去价值。
Intensive Care Med. 2018 Jul;44(7):1156-1158. doi: 10.1007/s00134-018-5151-7. Epub 2018 Apr 12.
9
The Intensive Care Medicine research agenda on critically ill oncology and hematology patients.重症肿瘤和血液学患者的重症监护医学研究议程。
Intensive Care Med. 2017 Sep;43(9):1366-1382. doi: 10.1007/s00134-017-4884-z. Epub 2017 Jul 19.
10
Focus on acute kidney injury.关注急性肾损伤。
Intensive Care Med. 2017 Sep;43(9):1421-1423. doi: 10.1007/s00134-017-4874-1. Epub 2017 Jul 3.
采用临床裁决验证细胞周期停滞生物标志物在急性肾损伤中的应用。
Am J Respir Crit Care Med. 2014 Apr 15;189(8):932-9. doi: 10.1164/rccm.201401-0077OC.
4
Time of injury affects urinary biomarker predictive values for acute kidney injury in critically ill, non-septic patients.受伤时间影响非脓毒症危重症患者急性肾损伤的尿生物标志物预测值。
BMC Nephrol. 2013 Dec 9;14:273. doi: 10.1186/1471-2369-14-273.
5
The nature and discriminatory value of urinary neutrophil gelatinase-associated lipocalin in critically ill patients at risk of acute kidney injury.危重症患者急性肾损伤风险中性粒细胞明胶酶相关载脂蛋白的性质和鉴别价值。
Intensive Care Med. 2013 Oct;39(10):1714-24. doi: 10.1007/s00134-013-3040-7. Epub 2013 Aug 6.
6
Diagnosis of acute kidney injury using functional and injury biomarkers: workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference.使用功能和损伤生物标志物诊断急性肾损伤：第十届急性透析质量倡议共识会议工作组声明
Contrib Nephrol. 2013;182:13-29. doi: 10.1159/000349963. Epub 2013 May 13.
7
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury.人类急性肾损伤中细胞周期阻滞生物标志物的发现与验证
Crit Care. 2013 Feb 6;17(1):R25. doi: 10.1186/cc12503.
8
Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature.尿液和血清生物标志物在急性肾损伤诊断中的应用：文献深入综述。
Nephrol Dial Transplant. 2013 Feb;28(2):254-73. doi: 10.1093/ndt/gfs380. Epub 2012 Oct 31.
9
New metrics for assessing diagnostic potential of candidate biomarkers.评估候选生物标志物诊断潜力的新指标。
Clin J Am Soc Nephrol. 2012 Aug;7(8):1355-64. doi: 10.2215/CJN.09590911. Epub 2012 Jun 7.
10
Imperfect gold standards for kidney injury biomarker evaluation.用于评估肾损伤生物标志物的不完美金标准。
J Am Soc Nephrol. 2012 Jan;23(1):13-21. doi: 10.1681/ASN.2010111124. Epub 2011 Oct 21.