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AKI biomarkers are poor discriminants for subsequent need for renal replacement therapy, but do not disqualify them yet.

作者信息

de Grooth Harm-Jan, Parienti Jean-Jacques, Schetz Miet

机构信息

Department of Intensive Care, VU University Medical Center, De Boelelaan 1118, 1081 HZ, Amsterdam, The Netherlands.

Department of Biostatistics and Clinical Research, Centre Hospitalo-Universistaire de Caen, Caen, France.

出版信息

Intensive Care Med. 2018 Jul;44(7):1156-1158. doi: 10.1007/s00134-018-5151-7. Epub 2018 Apr 12.

DOI:10.1007/s00134-018-5151-7
PMID:29651499
Abstract
摘要

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本文引用的文献

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Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis.用于急性肾损伤肾替代治疗预测的生物标志物:系统评价和荟萃分析。
Intensive Care Med. 2018 Mar;44(3):323-336. doi: 10.1007/s00134-018-5126-8. Epub 2018 Mar 14.
2
Validating benefit of biomarker-directed therapy for acute kidney injury: can you have your cake and eat it?验证生物标志物导向疗法对急性肾损伤的益处:鱼与熊掌能否兼得?
Intensive Care Med. 2017 Apr;43(4):578-580. doi: 10.1007/s00134-017-4710-7. Epub 2017 Feb 16.
3
Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial.
基于临床实验室平台检测中性粒细胞明胶酶相关脂质运载蛋白对急性肾损伤及其相关透析治疗需求的预测价值:系统评价和荟萃分析。
Am J Kidney Dis. 2020 Dec;76(6):826-841.e1. doi: 10.1053/j.ajkd.2020.05.015. Epub 2020 Jul 15.
4
Focus on critical care nephrology.专注于重症监护肾脏病学。
Intensive Care Med. 2019 Sep;45(9):1288-1291. doi: 10.1007/s00134-019-05679-x. Epub 2019 Jul 11.
5
Performance of Doppler-based resistive index and semi-quantitative renal perfusion in predicting persistent AKI: results of a prospective multicenter study.基于多普勒的阻力指数和半定量肾灌注在预测持续性 AKI 中的性能:一项前瞻性多中心研究的结果。
Intensive Care Med. 2018 Nov;44(11):1904-1913. doi: 10.1007/s00134-018-5386-3. Epub 2018 Oct 5.
通过在生物标志物识别的高危患者中实施 KDIGO 指南预防心脏手术相关 AKI:PrevAKI 随机对照试验。
Intensive Care Med. 2017 Nov;43(11):1551-1561. doi: 10.1007/s00134-016-4670-3. Epub 2017 Jan 21.
4
When to start renal replacement therapy in critically ill patients with acute kidney injury: comment on AKIKI and ELAIN.急性肾损伤的危重症患者何时开始肾脏替代治疗:对AKIKI和ELAIN研究的评论
Crit Care. 2016 Aug 6;20(1):245. doi: 10.1186/s13054-016-1424-0.
5
Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: The ELAIN Randomized Clinical Trial.早期与延迟启动肾脏替代治疗对急性肾损伤危重症患者死亡率的影响:ELAIN 随机临床试验。
JAMA. 2016;315(20):2190-9. doi: 10.1001/jama.2016.5828.
6
Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit.重症监护病房肾脏替代治疗的启动策略。
N Engl J Med. 2016 Jul 14;375(2):122-33. doi: 10.1056/NEJMoa1603017. Epub 2016 May 15.
7
Measurement of AKI biomarkers in the ICU: still striving for appropriate clinical indications.重症监护病房中急性肾损伤生物标志物的测量:仍在为合适的临床指征而努力。
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