Campos M S, López-Aliaga I, Barrionuevo M, Lisbona F, Coves F
Departamento de Fisiologia, Facultad de Farmacia, Universidad de Granada, Spain.
J Nutr Sci Vitaminol (Tokyo). 1989 Oct;35(5):511-21. doi: 10.3177/jnsv.35.511.
The nutritive utilization of calcium was studied in adult rats in which 50% of the distal small intestine (DSI) had been resected and in sham-operated controls one month and three months after the operation. Resection of half the DSI reduced the digestive utilization of Ca as reflected by mineral content in bone. Three months after resection, nutritive utilization of Ca had still not recovered. Feeding the resected rats with a diet in which fat content consisted of equal parts of medium-chain triglycerides (MCT), sunflower seed oil, and olive oil failed to improve nutritive utilization of Ca after one or three months in comparison with a diet containing olive oil as the only source of lipids. Supplementation with vitamin D3 (0.04 mg/100 g diet) enhanced nutritive utilization of Ca in resected rats after one month, the beneficial effect becoming much more patent after three months. At the dose used, vitamin D3 favored calcium deposition in bone tissue. Serum levels of Ca remained unchanged under all experimental conditions, both one month and three months after 50% DSI resection.
研究了成年大鼠在切除远端小肠（DSI）的50%后以及假手术对照组在术后1个月和3个月时钙的营养利用情况。切除一半的DSI会降低钙的消化利用率，这可通过骨矿物质含量反映出来。切除术后3个月，钙的营养利用率仍未恢复。与以橄榄油作为唯一脂质来源的饮食相比，给切除术后的大鼠喂食脂肪含量由等量中链甘油三酯（MCT）、葵花籽油和橄榄油组成的饮食，在1个月或3个月后均未能提高钙的营养利用率。补充维生素D3（0.04 mg/100 g饮食）在1个月后提高了切除术后大鼠钙的营养利用率，3个月后这种有益效果变得更加明显。在所使用的剂量下，维生素D3有利于钙在骨组织中的沉积。在50% DSI切除术后1个月和3个月的所有实验条件下，血清钙水平均保持不变。
