Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine and i-Lab, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, China.
College of Biological Science and Technology, Fuzhou University, Fuzhou, 350108, China.
Small. 2015 Jun 3;11(21):2505-9. doi: 10.1002/smll.201401512. Epub 2015 Jan 22.
Site-selective biomineralization of Au nanostructures in the interior channel of Tobacco Mosaic Virus (TMV) is achieved by mutating threonine 103 in TMV to cysteine (T103C-TMV) to introduce the strong coordination interaction between the arrayed sulfhydryl ligands and gold species. By finely tuning the reaction conditions, Au nanoparticle chains and Au nanorods are successfully and exclusively synthesized inside the T103C-TMV nanotubes.
通过将烟草花叶病毒（TMV）中的苏氨酸 103 突变为半胱氨酸（T103C-TMV），以引入排列的巯基配体与金物种之间的强配位相互作用，实现了 Au 纳米结构在 TMV 内部通道中的选择性生物矿化。通过精细调节反应条件，成功且专一地在 T103C-TMV 纳米管内合成了 Au 纳米链和 Au 纳米棒。
