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[大肠杆菌噬菌体受体。参与作为噬菌体受体的特异性转运的小外膜孔蛋白和蛋白质]

[Escherichia coli phage receptors. Minor porins and proteins participating in the specific transport as phage receptors].

作者信息

Likhacheva N A, Sineokiĭ S P

出版信息

Mol Gen Mikrobiol Virusol. 1989 Dec(12):3-12.

PMID:2561376
Abstract

Except for the main porin proteins OmpC and OmpF there exist the membrane proteins participating in the transport of specific substrates: phosphates, nucleosides, iron, vitamin B12, maltose and maltodextrins, that also play the role of phage receptors. Some phages use as receptors the porins determined by the genes of lambdoid prophages. LamB protein that serves receptor for phage lambda exposes the amino acids sequence on the outer surface of membranes that participates in phage adsorption. The sequence is similar to tetrapeptide of fibronectin responsible for binding with the surface of cellular receptor in eucaryotes.

摘要

除了主要的孔蛋白OmpC和OmpF外,还存在参与特定底物运输的膜蛋白:磷酸盐、核苷、铁、维生素B12、麦芽糖和麦芽糊精,它们也起到噬菌体受体的作用。一些噬菌体将由λ样原噬菌体基因决定的孔蛋白用作受体。作为噬菌体λ受体的LamB蛋白在膜的外表面暴露参与噬菌体吸附的氨基酸序列。该序列类似于负责与真核生物中细胞受体表面结合的纤连蛋白四肽。

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