Ashwood Karen L, Tye Charlotte, Azadi Bahare, Cartwright Sally, Asherson Philip, Bolton Patrick
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK,
J Autism Dev Disord. 2015 Jul;45(7):2235-42. doi: 10.1007/s10803-014-2352-y.
Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) often co-occur. Children with ASD and ADHD demonstrate deficits in adaptive functioning, yet pure and comorbid groups have not been directly compared. Vineland Adaptive Behaviour Scales (VABS-II) data were examined in boys with ASD (n = 17), ADHD (n = 31) and ASD + ADHD (n = 38). Results demonstrated lower socialisation and composite scores and greater discrepancy between cognitive and adaptive abilities in the ASD + ADHD group compared to the ADHD-only group. Significant associations were shown between reduced adaptive functioning and autism symptoms, but not ADHD symptoms. Children with ASD + ADHD present with exacerbated impairments in adaptive functioning relative to children with ADHD, associated with ASD symptoms. Disentangling variation in adaptive skills may aid the assessment of complex cases.
自闭症谱系障碍(ASD)和注意力缺陷多动障碍(ADHD)常常同时出现。患有ASD和ADHD的儿童在适应性功能方面存在缺陷,但尚未对单纯患病组和共病组进行直接比较。对患有ASD(n = 17)、ADHD(n = 31)和ASD + ADHD(n = 38)的男孩的文兰适应行为量表(VABS-II)数据进行了检查。结果表明,与仅患有ADHD的组相比,ASD + ADHD组的社交能力和综合得分更低,认知能力与适应能力之间的差异更大。适应性功能降低与自闭症症状之间存在显著关联,但与ADHD症状无关。与患有ADHD的儿童相比,患有ASD + ADHD的儿童在适应性功能方面存在更严重的损害,这与ASD症状有关。区分适应性技能的差异可能有助于评估复杂病例。