口腔、生殖器或泌尿系统癌症患者手术后单纯疱疹病毒1型在唾液中的排出情况。

Shedding of herpes simplex virus type 1 into saliva after surgery for oral and genital or urological cancer patients.

作者信息

Kameyama T, Haikata K, Nakamura Y, Murase H, Yamamoto S

出版信息

Kurume Med J. 1989;36(3):117-21. doi: 10.2739/kurumemedj.36.117.

DOI:10.2739/kurumemedj.36.117

Abstract

The shedding of herpes simplex virus type-1 (HSV-1) into the saliva was compared in 28 patients with oral cancer and 26 patients with genital or urological cancer. All subjects tested positive for HSV-1 specific antibody. A statistically significant (p less than 0.001) difference was found: infectious viruses were isolated from 12 (39.8%) of the oral cancer patients versus only 2 (7.6%) of the genital or urological patients. This indicates that direct stimulation of peripheral nerves during surgery was responsible for the greater reactivation of HSV-1.

摘要

对28例口腔癌患者和26例生殖器或泌尿系统癌症患者的单纯疱疹病毒1型（HSV-1）唾液排出情况进行了比较。所有受试者的HSV-1特异性抗体检测均呈阳性。发现了具有统计学意义（p<0.001）的差异：12例（39.8%）口腔癌患者分离出感染性病毒，而生殖器或泌尿系统癌症患者中只有2例（7.6%）分离出感染性病毒。这表明手术期间对周围神经的直接刺激导致了HSV-1的更多再激活。