El Wahidi M, El Amraoui B, El Amraoui M, Bamhaoud T
Laboratoire contrôle qualité en bio-industrie et molécules bio-actives, faculté des sciences, université Chouaib Doukkali, BP 20, 24000 El-Jadida, Morocco.
Laboratoire contrôle qualité en bio-industrie et molécules bio-actives, faculté des sciences, université Chouaib Doukkali, BP 20, 24000 El-Jadida, Morocco; Faculté polydisciplinaire de Taroudant, université Ibn Zohr, BP 271, 83000 Taroudant, Morocco.
Ann Pharm Fr. 2015 May;73(3):190-6. doi: 10.1016/j.pharma.2014.12.005. Epub 2015 Jan 19.
The aim of this work is the screening of the antimicrobial activity of seaweed extracts against pathogenic bacteria and yeasts. The antimicrobial activity of the dichloromethane and ethanol extracts of ten marine macroalgae collected from the Moroccan's Atlantic coast (El-Jadida) was tested against two Gram+ (Bacillus subtilis and Staphylococcus aureus) and two Gram- (Escherichia coli and Pseudomonas aeruginosa) human pathogenic bacteria, and against two pathogenic yeasts (Candida albicans and Cryptococcus neoformans) using the agar disk-diffusion method. Seven algae (70%) of ten seaweeds are active against at least one pathogenic microorganisms studied. Five (50%) are active against the two studied yeast with an inhibition diameter greater than 15 mm for Cystoseira brachycarpa. Six (60%) seaweeds are active against at least one studied bacteria with five (50%) algae exhibiting antibacterial inhibition diameter greater than 15 mm. Cystoseira brachycarpa, Cystoseira compressa, Fucus vesiculosus, and Gelidium sesquipedale have a better antimicrobial activity with a broad spectrum antimicrobial and are a potential source of antimicrobial compounds and can be subject of isolation of the natural antimicrobials.
这项工作的目的是筛选海藻提取物对病原菌和酵母菌的抗菌活性。采用琼脂扩散法，对从摩洛哥大西洋海岸（埃尔贾迪达）采集的十种大型海藻的二氯甲烷和乙醇提取物的抗菌活性进行了测试，受试对象为两种革兰氏阳性菌（枯草芽孢杆菌和金黄色葡萄球菌）、两种革兰氏阴性菌（大肠杆菌和铜绿假单胞菌）以及两种致病酵母菌（白色念珠菌和新型隐球菌）。十种海藻中有七种（70%）对至少一种受试致病微生物具有活性。五种（50%）对两种受试酵母菌具有活性，短节囊链藻对酵母菌的抑菌圈直径大于15毫米。六种（60%）海藻对至少一种受试细菌具有活性，五种（5�%）海藻的抑菌圈直径大于15毫米。短节囊链藻、扁囊链藻、墨角藻和长茎石花菜具有较好的抗菌活性，抗菌谱广，是抗菌化合物的潜在来源，可用于天然抗菌剂的分离。
