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单吻合口或迷你胃旁路手术:5年随访后的长期结果及生活质量

Single anastomosis or mini-gastric bypass: long-term results and quality of life after a 5-year follow-up.

作者信息

Bruzzi Matthieu, Rau Cédric, Voron Thibault, Guenzi Martino, Berger Anne, Chevallier Jean-Marc

机构信息

Hôpital Européen Georges Pompidou, Paris, France.

Hôpital Européen Georges Pompidou, Paris, France.

出版信息

Surg Obes Relat Dis. 2015 Mar-Apr;11(2):321-6. doi: 10.1016/j.soard.2014.09.004. Epub 2014 Sep 16.

Abstract

BACKGROUND

Laparoscopic mini-gastric bypass (LMGB) is an alternative to the laparoscopic Roux-en-Y gastric bypass (LRYGB), which is considered to be the gold standard in the treatment of morbid obesity.

OBJECTIVES

Present 5-year results of 175 patients who had undergone a LMGB between October 2006 and October 2008.

SETTING

University public hospital, France.

METHODS

Complete follow-up was available in 126 of 175 patients (72%) who had LMGB. Mortality, morbidity, weight loss, co-morbidities, and quality of life were assessed. Weight loss was determined as a change in body mass index (BMI) and percent excess BMI loss (%EBMIL). Quality of life in the treatment group was analyzed using the Gastrointestinal Quality of Life Index (GIQLI) and was compared with a retrospectively case matched preoperative control group.

RESULTS

There were no deaths. Thirteen patients (10.3%) developed major complications. Marginal ulcers occurred in 4% of patients. Incapacitating biliary reflux developed in 2 (1.6%) who required conversion into RYGB. Gastric pouch dilation occurred in 4 patients (3.2%) and inadequate weight loss with severe malnutrition in 2 (1.6%). At 5 years, mean BMI was 31±6 kg/m(2) and mean %EBMIL was 71.5%±26.5%. Postoperative GIQLI score of the treatment group was significantly higher than preoperative score of the control group (110.3±17.4 versus 92.5±15.9, P<.001). Social, psychological, and physical functions were increased significantly. No significant differences were found in gastroesophageal reflux or diarrhea symptoms between the 2 groups. Long-term follow-up showed an improvement in all co-morbidities.

CONCLUSIONS

At 5 years, LMGB was safe, effective, and provided interesting quality of life results.

摘要

背景

腹腔镜迷你胃旁路术(LMGB)是腹腔镜Roux-en-Y胃旁路术(LRYGB)的一种替代术式,LRYGB被认为是治疗病态肥胖的金标准。

目的

呈现2006年10月至2008年10月间接受LMGB手术的175例患者的5年随访结果。

地点

法国大学公立医院。

方法

175例行LMGB手术的患者中有126例(72%)获得了完整随访。评估了死亡率、发病率、体重减轻情况、合并症及生活质量。体重减轻通过体重指数(BMI)变化和超重BMI丢失百分比(%EBMIL)来确定。治疗组的生活质量采用胃肠道生活质量指数(GIQLI)进行分析,并与回顾性病例匹配的术前对照组进行比较。

结果

无死亡病例。13例患者(10.3%)发生了严重并发症。4%的患者出现边缘性溃疡。2例患者(1.6%)发生致残性胆汁反流,需要转为RYGB手术。4例患者(3.2%)出现胃囊扩张,2例患者(1.6%)体重减轻不足且伴有严重营养不良。5年后,平均BMI为31±6kg/m²,平均%EBMIL为71.5%±26.5%。治疗组术后GIQLI评分显著高于对照组术前评分(110.3±17.4对92.5±15.9,P<0.001)。社会、心理和身体功能均显著改善。两组间胃食管反流或腹泻症状无显著差异。长期随访显示所有合并症均有改善。

结论

5年时,LMGB安全、有效,并能带来令人满意的生活质量结果。

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