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用皮质类固醇治疗的严重出血性黄疸型问号钩端螺旋体感染伴肝、肾、肺受累

Severe Leptospira interrogans serovar Icterohaemorrhagiae infection with hepato-renal-pulmonary involvement treated with corticosteroids.

作者信息

Schulze Marco H, Raschel Heribert, Langen Heinz-Jakob, Stich August, Tappe Dennis

机构信息

Institute for Medical Microbiology, University Medical Centre Göttingen Kreuzbergring 57, D-37075, Göttingen, Germany ; Department of Tropical Medicine, Medical Mission Hospital Salvatorstrasse 7, D-97074, Würzburg, Germany.

Bavarian Health and Food Safety Authority Veterinärstrasse 2, D-85764, Oberschleissheim, Germany.

出版信息

Clin Case Rep. 2014 Oct;2(5):191-6. doi: 10.1002/ccr3.91. Epub 2014 Sep 15.

DOI:10.1002/ccr3.91
PMID:25614810
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4302624/
Abstract

The traditional concept of immediate antibiotic treatment in suspected leptospirosis seems to be especially important for patients up to day 4 of clinical illness. As immune mechanisms probably play a crucial role in advanced leptospirosis with presumed pulmonary hemorrhages, patients might benefit from corticosteroids or other immunosuppressive agents beside antibiotics.

摘要

对于疑似钩端螺旋体病的患者，在临床发病的第4天内进行即时抗生素治疗这一传统观念似乎尤为重要。由于免疫机制可能在伴有推测性肺出血的晚期钩端螺旋体病中起关键作用，除抗生素外，患者可能会从使用皮质类固醇或其他免疫抑制剂中获益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd2c/4302624/17961d08f245/ccr30002-0191-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd2c/4302624/8c098cf11210/ccr30002-0191-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd2c/4302624/17961d08f245/ccr30002-0191-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd2c/4302624/8c098cf11210/ccr30002-0191-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd2c/4302624/17961d08f245/ccr30002-0191-f2.jpg

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