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体外受精尝试后发生的输卵管妊娠合并子宫内膜癌

Tubal pregnancy associated with endometrial carcinoma after in vitro fertilization attempts.

作者信息

Bayoglu Tekin Yesim, Guvendag Guven Emine Seda, Sehitoglu Ibrahim, Guven Suleyman

机构信息

Recep Tayyip Erdogan Universitesi, Tıp Fakultesi Dekanlığı, Islampaşa Mahallesi, Merkez, 53020 Rize, Turkey ; Department of Gynecology and Obstetrics, School of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Turkey.

Department of Gynecology and Obstetrics, School of Medicine, Recep Tayyip Erdogan University, 53020 Rize, Turkey.

出版信息

Case Rep Obstet Gynecol. 2014;2014:481380. doi: 10.1155/2014/481380. Epub 2014 Dec 28.

DOI:10.1155/2014/481380
PMID:25614844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4295414/
Abstract

Endometrial carcinoma is rarely seen during reproductive ages and commonly related to infertility, polycystic ovarian syndrome (PCOS), and obesity. Pregnancy associated endometrial carcinoma is even rarer and this is the second case reported in the literature concerning tubal pregnancy associated endometrial carcinoma. We present a case of a 36-year-old woman with a history of PCOS, infertility, and several attempts of ovulation induction and in vitro fertilization, who was diagnosed with tubal pregnancy and a well differentiated endometrial carcinoma. We also review the literature about pregnancy associated endometrial carcinoma in the first trimester.

摘要

子宫内膜癌在育龄期很少见,通常与不孕、多囊卵巢综合征(PCOS)和肥胖有关。妊娠相关的子宫内膜癌更为罕见,这是文献中报道的第二例关于输卵管妊娠合并子宫内膜癌的病例。我们报告一例36岁女性,有PCOS、不孕病史,曾多次尝试诱导排卵和体外受精,被诊断为输卵管妊娠和高分化子宫内膜癌。我们还回顾了关于孕早期妊娠相关子宫内膜癌的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d98/4295414/acd04aac65b9/CRIOG2014-481380.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d98/4295414/acd04aac65b9/CRIOG2014-481380.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d98/4295414/acd04aac65b9/CRIOG2014-481380.001.jpg

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本文引用的文献

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Controlled ovarian hyperstimulation for IVF: impact on ovarian, endometrial and cervical cancer--a systematic review and meta-analysis.控制性卵巢刺激用于体外受精:对卵巢癌、子宫内膜癌和宫颈癌的影响——系统评价和荟萃分析。
Hum Reprod Update. 2013 Mar-Apr;19(2):105-23. doi: 10.1093/humupd/dms051. Epub 2012 Dec 18.
2
Concurrent endometrial adenocarcinoma and an early pregnancy loss.
Arch Gynecol Obstet. 2012 Oct;286(4):1089-90. doi: 10.1007/s00404-012-2400-9. Epub 2012 Jun 12.
3
The progesterone receptor regulates implantation, decidualization, and glandular development via a complex paracrine signaling network.孕激素受体通过复杂的旁分泌信号网络调节着床、蜕膜化和腺体发育。
Mol Cell Endocrinol. 2012 Jun 24;357(1-2):108-18. doi: 10.1016/j.mce.2011.10.028. Epub 2011 Nov 17.
4
Incidental endometrial adenocarcinoma in early pregnancy: a case report and review of the literature.早孕期偶然发现的子宫内膜腺癌:病例报告及文献复习。
Int J Gynecol Cancer. 2009 Dec;19(9):1580-4. doi: 10.1111/IGC.0b013e3181a841a7.
5
Gynaecologic cancer complicating pregnancy: an overview.妇科癌症合并妊娠:概述。
Best Pract Res Clin Obstet Gynaecol. 2010 Feb;24(1):61-79. doi: 10.1016/j.bpobgyn.2009.08.001. Epub 2009 Sep 8.
6
GnRH agonist versus GnRH antagonist in ovarian stimulation: the role of endometrial receptivity.促性腺激素释放激素激动剂与拮抗剂在卵巢刺激中的应用:子宫内膜容受性的作用
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7
Multicenter phase II study of fertility-sparing treatment with medroxyprogesterone acetate for endometrial carcinoma and atypical hyperplasia in young women.醋酸甲羟孕酮用于年轻女性子宫内膜癌和非典型增生保留生育功能治疗的多中心II期研究。
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