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[应用图像细胞术评估胃发育异常及癌组织中的DNA含量]

[Evaluation of DNA content in gastric dysplasia and carcinoma by image cytometry].

作者信息

Shao L, Lei D N

出版信息

Zhonghua Bing Li Xue Za Zhi. 1989 Dec;18(4):254-6.

PMID:2561533
Abstract

In 30 cases of gastric dysplasia and 10 cases of gastric carcinoma, DNA content was studied by IBAS image analysis system. The mean DNA level increased steadily with the advance of histologic gradation, and the highest DNA content was observed in gastric carcinoma. No case of aneuploidy was found in mild dysplasia. In moderate dysplasia, aneuploid cells were occasionally encountered. Severe dysplasia had a lower percentage (4.48%), and gastric carcinoma was characterized by a high percentage of aneuploid cells (14.54%).

摘要

应用IBAS图像分析系统对30例胃发育异常和10例胃癌进行DNA含量测定。结果显示,随着组织学分级的升高,DNA平均含量呈逐渐上升趋势,其中胃癌的DNA含量最高。轻度发育异常均未见非整倍体细胞;中度发育异常可见少量非整倍体细胞;重度发育异常非整倍体细胞所占比例较低(4.48%);胃癌非整倍体细胞所占比例较高(14.54%)。

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