Cortez Victor S, Robinette Michelle L, Colonna Marco
Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63018, United States.
Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63018, United States.
Curr Opin Immunol. 2015 Feb;32:71-7. doi: 10.1016/j.coi.2015.01.004. Epub 2015 Jan 20.
Here, we illustrate the complexity of ILC subsets and discuss novel functions, focusing on emerging mechanisms of crosstalk with other immune cells and the microbiota. Furthermore, we highlight recent insights into the development of ILCs, including the common pathways they share as well as points of divergence between ILC groups and subsets.
在此,我们阐述了ILC亚群的复杂性,并讨论了其新功能,重点关注与其他免疫细胞和微生物群相互作用的新兴机制。此外,我们强调了对ILC发育的最新见解,包括它们共有的常见途径以及ILC群体和亚群之间的差异点。