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珊瑚多孔羟基磷灰石作为正颌外科骨移植替代物:24个月随访结果。

Coralline porous hydroxyapatite as a bone graft substitute in orthognathic surgery: 24-month follow-up results.

作者信息

Moenning J E, Wolford L M

出版信息

Int J Adult Orthodon Orthognath Surg. 1989;4(2):105-17.

PMID:2561745
Abstract

A 24-month postsurgical follow-up evaluation was performed on 49 patients (20 males and 29 females; mean age 26 years [range 9 to 52 years]) who had undergone orthognathic surgery in which coralline porous block hydroxyapatite (PBHA) was used as a bone graft substitute. Followup ranged from 23 to 45 months (average 27 months). One surgeon implanted all 215 blocks: 189 blocks to the maxilla, 19 blocks to the mandible, and seven blocks to the midfacial region. Of the 215 implants, 135 were positioned directly adjacent to the maxillary sinus. Nine patients had postsurgical complications: three developed sinusitis, which was treated with antibiotics and decongestants, four had midpalatal implants exposed intraorally during surgery that later required removal, one had a slight displacement of a mandibular implant that has remained in place, and one had an interdental implant exposed that was recontoured and covered with tissue. At the 24-month followup or later, only one of the 49 patients had complications or symptoms associated months postsurgery. These results strongly support the use of coralline PBHA along with bone plate fixation to provide predictable stability in orthognathic surgery.

摘要

对49例患者(20例男性,29例女性;平均年龄26岁[范围9至52岁])进行了术后24个月的随访评估,这些患者接受了正颌手术,术中使用珊瑚多孔块状羟基磷灰石(PBHA)作为骨移植替代物。随访时间为23至45个月(平均27个月)。所有215块植入物均由一名外科医生植入:189块植入上颌骨,19块植入下颌骨,7块植入面中部区域。在这215枚植入物中,135枚直接位于上颌窦附近。9例患者出现术后并发症:3例发生鼻窦炎,经抗生素和减充血剂治疗;4例患者术中腭中部植入物在口腔内暴露,后来需要取出;1例下颌植入物有轻微移位,但仍留在原位;1例牙间植入物暴露,对其进行了重新塑形并覆盖组织。在术后24个月或更晚的随访中,49例患者中只有1例出现与手术相关的并发症或症状。这些结果有力地支持了在正颌手术中使用珊瑚PBHA并结合骨板固定以提供可预测的稳定性。

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