Ni Jianqiang, Zheng Yanping, Liu Ning, Wang Xin, Fang Xiutong, Phukan Rishabh, Wood Kirkham B
Department of Orthopedics, Qilu Hospital, Shandong University, Shandong, China.
Eur Spine J. 2015 Apr;24(4):791-9. doi: 10.1007/s00586-014-3745-5. Epub 2015 Jan 25.
The aim of this study was to evaluate the radiographic characteristics of polyetheretherketone (PEEK) cages packed with adjacent vertebral autograft material in lumbar anterior lumbar interbody fusion (ALIF) in spinal deformity long fusion surgeries.
This is a retrospective radiographic study. From April 2008 to April 2012, 40 patients (5 males and 35 females, mean age 67 ± 9 years) with coronal and/or sagittal spine deformities underwent staged corrective surgery combined with lumbar ALIF using PEEK cages at the L3-L4, L4-L5 or L5-S1 segment with posterior long (≥ 4 levels) instrumentation. The mean follow-up time was 27.5 months (13-49 months). We examined the interbody fusion rate and cage subsidence at 3 months postoperatively and final follow-up. Additionally, we evaluated the distance of cage migration at final follow-up and the improvement in lumbar lordosis. The rate of "collapse" of the adjacent vertebra where the autograft was harvested was assessed at the final follow-up. Finally, we examined the cage-related postoperative complications in this series.
Solid interbody fusion was achieved in 96.4 % (81/84) of the levels at the final follow-up. A mild forward cage migration was observed, and the mean migration distance at final follow-up was 0.83 mm in L3/4, 0.36 mm in L4/5 and 0.55 mm in L5/S1. There was cage subsidence observed in 8.3 % (7/84) of the levels. In all patients, the PEEK cage maintained a significant increase in segmental lordosis at all postoperative visits. However, a mild reduction in segmental lordosis still occurred with time. The adjacent lumbar vertebral bodies where the autografts were harvested appeared to be intact in height radiologically at the final follow-up. There were no postoperative complications due to bone harvesting or cage insertion. Proximal junctional kyphosis was found in one patient who underwent a subsequent revision surgery.
The use of lumbar ALIF with PEEK cages and adjacent vertebral autografts in spinal deformity long fusion surgeries is an effective and safe procedure. The allograft filler is safe and effective in maintaining the shape of harvested vertebrae. Additional long-term follow-up studies are needed to further justify its use.
本研究旨在评估在脊柱畸形长节段融合手术的腰椎前路椎间融合术(ALIF)中,填充相邻椎体自体移植材料的聚醚醚酮(PEEK)椎间融合器的影像学特征。
这是一项回顾性影像学研究。2008年4月至2012年4月,40例(5例男性和35例女性,平均年龄67±9岁)患有冠状面和/或矢状面脊柱畸形的患者接受了分期矫正手术,并在L3-L4、L4-L5或L5-S1节段使用PEEK椎间融合器进行腰椎ALIF,并采用后路长节段(≥4个节段)内固定。平均随访时间为27.5个月(13-49个月)。我们在术后3个月和末次随访时检查椎间融合率和椎间融合器下沉情况。此外,我们评估了末次随访时椎间融合器的移位距离以及腰椎前凸的改善情况。在末次随访时评估取自体骨的相邻椎体的“塌陷”率。最后,我们检查了本系列中与椎间融合器相关的术后并发症。
在末次随访时,96.4%(81/84)的节段实现了坚实的椎间融合。观察到椎间融合器有轻度向前移位,末次随访时L3/4节段的平均移位距离为0.83mm,L4/5节段为0.36mm,L5/S1节段为0.55mm。8.3%(7/84)的节段出现了椎间融合器下沉。在所有患者中,PEEK椎间融合器在术后各次随访时均使节段性前凸显著增加。然而,节段性前凸仍随时间有轻度降低。在末次随访时,取自体骨的相邻腰椎椎体在影像学上高度似乎保持完整。没有因取骨或植入椎间融合器而导致的术后并发症。在1例接受后续翻修手术的患者中发现了近端交界性后凸。
在脊柱畸形长节段融合手术中使用带PEEK椎间融合器和相邻椎体自体骨的腰椎ALIF是一种有效且安全的手术方法。同种异体骨填充物在维持取骨椎体形状方面是安全有效的。需要进一步的长期随访研究来进一步证明其使用的合理性。