Ghanem Ali M, Mansour Abdulrab, Exton Rebecca, Powell Jonathan, Mashhadi Syed, Bulstrode Neil, Smith Gillian
Department of Plastic Surgery, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK; Academic Plastic Surgery Group, Centre for Cutaneous Research, Blizard Institute, Barts and the London School of Medicine and Dentistry, 4 Newark St, London, E1 2AT, UK.
Department of Plastic Surgery, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK.
J Plast Reconstr Aesthet Surg. 2015 Apr;68(4):505-18. doi: 10.1016/j.bjps.2014.12.029. Epub 2015 Jan 8.
Extravasation is an iatrogenic injury that may produce soft tissue necrosis requiring surgical reconstruction (Rose et al., 2008) and (Goon et al., 2006). Previous review of extravasation injuries within our hospital showed that early referral to plastic surgeons and washout of high-risk cases lead to favourable outcome in 86% of patients (Gault, 1993). Hospital-wide guidelines were introduced in 2005. This paper closes the audit loop by evaluating extravasation injuries outcome following the introduction of these guidelines.
All patients referred to the plastic surgery department for extravasation injuries between October 2008 and October 2009 were reviewed. A favourable outcome was defined as resolution without tissue loss requiring surgical reconstruction. Patients were excluded if they sustained the extravasation in other institution.
A total of 82 extravasation injuries in 78 patients were reviewed during the audit period. Mean age was 3.2 years (Median 0.2 years, Minimum 0 day, and maximum 16.7 years). The injuries were more frequent on the left half of the body (52%) and involving the upper limbs (59%). Mean time to referral was 8 h, with 60% of patients referred within 6 h of the injury, 30% in 6-12 h, and 10% referred after more than 12 h 26% of the injuries required washout treatment - the rest was treated conservatively. Tissue necrosis occurred in 3 cases (4%) but required no surgical intervention due to the small area affected.
Our audit showed an improved outcome of extravasation injury following introduction of hospital-wide guidelines of early referral to specialist team and washout of high-risk cases.
药物外渗是一种医源性损伤,可能导致软组织坏死,需要进行手术重建(罗斯等人,2008年)以及(古恩等人,2006年)。此前对我院内药物外渗损伤的回顾显示,早期转诊至整形外科医生并对高危病例进行冲洗,86%的患者获得了良好的治疗效果(高尔特,1993年)。2005年引入了全院范围的指导方针。本文通过评估这些指导方针实施后药物外渗损伤的治疗效果来完成审计循环。
对2008年10月至2009年10月间转诊至整形外科治疗药物外渗损伤的所有患者进行了回顾。良好的治疗效果定义为损伤消退,无需进行组织丢失的手术重建。如果患者在其他机构发生药物外渗,则将其排除。
在审计期间,共对78例患者的82次药物外渗损伤进行了回顾。平均年龄为3.2岁(中位数0.2岁,最小0天,最大16.7岁)。损伤在身体左侧更为常见(52%),且涉及上肢(59%)。平均转诊时间为8小时,60%的患者在受伤后6小时内转诊,30%在6至12小时内转诊,10%在超过12小时后转诊。26%的损伤需要冲洗治疗,其余采用保守治疗。3例(4%)发生了组织坏死,但由于受影响面积较小,无需手术干预。
我们的审计显示,在引入全院范围的早期转诊至专科团队并对高危病例进行冲洗的指导方针后,药物外渗损伤的治疗效果有所改善。