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乳腺标本X线片上应观察什么:经验教训

What to look for on a breast specimen radiograph: lessons learnt.

作者信息

Taylor Donna

机构信息

Department of Radiology, Royal Perth Hospital, Perth, Western Australia, Australia School of Surgery, University of Western Australia, Crawley, Western Australia.

出版信息

BMJ Case Rep. 2015 Jan 23;2015:bcr2014206827. doi: 10.1136/bcr-2014-206827.

DOI:10.1136/bcr-2014-206827
PMID:25618875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4307085/
Abstract

Two women underwent stereotactic sampling of mammographically detected lesions with insertion of breast biopsy markers. Localisation of the malignant lesions was performed using iodine 125 seeds, with bracketing of the edges of the larger lesion. The seeds/lesions were located and excised using a γ probe. Liga clips attached to peripheral sutures at the edges of the specimen enabled radiographic orientation. Surgeon and radiologist found the specimen radiographs difficult to interpret. In one case the surgeon thought the lesion had been removed, mistaking the iodine seed for the biopsy marker. The radiologist noted absence of the biopsy marker and marginal calcifications but was concerned the seed was absent. Widening the window level allowed seed identification, revealing a characteristic rectangular radiolucent area in what had been interpreted as a Liga clip. Correct interpretation of the findings helped guide lesion removal, intraoperative margin re-excision and confirmed (125)I seed retrieval.

摘要

两名女性接受了乳腺钼靶检测病变的立体定向采样,并插入了乳腺活检标记物。使用碘125种子对恶性病变进行定位,将较大病变的边缘进行标记。使用γ探头定位并切除种子/病变。标本边缘外周缝合线上附着的结扎夹可实现放射学定位。外科医生和放射科医生发现标本X线片难以解读。在一个病例中,外科医生认为病变已被切除,将碘种子误认为活检标记物。放射科医生注意到活检标记物缺失且边缘有钙化,但担心种子也缺失。加宽窗宽后可识别种子,在原本被解读为结扎夹的部位发现一个特征性的矩形透光区。对检查结果的正确解读有助于指导病变切除、术中切缘再次切除并确认(125)I种子取出。

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引用本文的文献

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本文引用的文献

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Breast. 2013 Aug;22(4):383-8. doi: 10.1016/j.breast.2013.04.016. Epub 2013 May 11.
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Radioactive seed localization for nonpalpable breast lesions: review of 1,000 consecutive procedures at a single institution.放射性粒子定位在触诊阴性乳腺病变中的应用:单一机构 1000 例连续病例的回顾性研究。
Ann Surg Oncol. 2011 Oct;18(11):3096-101. doi: 10.1245/s10434-011-1910-1. Epub 2011 Sep 27.
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Radioactive seed localization of breast lesions: an adequate localization method without seed migration.放射性粒子定位乳腺病变:一种无粒子迁移的充分定位方法。
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A multicentered, randomized, controlled trial comparing radioguided seed localization to standard wire localization for nonpalpable, invasive and in situ breast carcinomas.一项多中心、随机、对照临床试验,旨在比较放射性粒子定位与标准导丝定位在不可触及、浸润性和原位乳腺癌中的应用。
Ann Surg Oncol. 2011 Nov;18(12):3407-14. doi: 10.1245/s10434-011-1699-y. Epub 2011 Apr 30.
5
Systematic review of radioguided surgery for non-palpable breast cancer.放射性导向手术治疗不可触及性乳腺癌的系统评价。
Eur J Surg Oncol. 2011 May;37(5):388-97. doi: 10.1016/j.ejso.2011.01.018. Epub 2011 Feb 17.
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Strategies for localisation of impalpable breast lesions.触诊阴性乳腺病灶的定位策略。
Breast. 2011 Jun;20(3):246-53. doi: 10.1016/j.breast.2011.01.007. Epub 2011 Feb 1.
7
Breast surgical specimen radiographs: how reliable are they?乳腺外科标本 X 光片:它们有多可靠?
Eur J Radiol. 2011 Aug;79(2):245-9. doi: 10.1016/j.ejrad.2010.02.012. Epub 2010 Mar 20.
8
Current status of radioactive seed for localization of non palpable breast lesions.不可触及乳腺病变放射性定位种子的现状。
Am J Surg. 2010 Apr;199(4):522-8. doi: 10.1016/j.amjsurg.2009.05.019. Epub 2009 Dec 2.
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