艾滋病相关的卡波西肉瘤：其发病机制的分子模型
AIDS-associated Kaposi's sarcoma: a molecular model for its pathogenesis.
作者信息
Ensoli B, Salahuddin S Z, Gallo R C
机构信息
Laboratory of Tumor Cell Biology, National Cancer Institute, NIH, Bethesda, Maryland 20892.
出版信息
Cancer Cells. 1989 Nov;1(3):93-6.
PMID:2561910
Abstract
Kaposi's sarcoma is a mesenchymal tumor that is frequently observed in AIDS patients. Although the tumor is clearly associated with HIV-1 infection, little is known about the molecular events underlying its pathogenesis. Here we consider the potential roles of specific cytokines and the virally encoded tat product in inducing the tumor.
摘要
卡波西肉瘤是一种间充质肿瘤，常见于艾滋病患者。尽管该肿瘤与HIV-1感染密切相关，但其发病机制背后的分子事件却鲜为人知。在此，我们探讨特定细胞因子和病毒编码的tat产物在诱导肿瘤方面的潜在作用。
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