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创伤后死亡的四峰分布表明,严重损伤是一种潜在的终末期疾病。

Quadrimodal distribution of death after trauma suggests that critical injury is a potentially terminal disease.

作者信息

Santry Heena P, Psoinos Charles M, Wilbert Christopher J, Flahive Julie M, Kroll-Desrosiers Aimee R, Emhoff Timothy A, Kiefe Catarina I

机构信息

Department of Surgery, University of Massachusetts Medical School, Worcester, MA, USA; Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.

Department of Surgery, University of Massachusetts Medical School, Worcester, MA, USA.

出版信息

J Crit Care. 2015 Jun;30(3):656.e1-7. doi: 10.1016/j.jcrc.2015.01.003. Epub 2015 Jan 8.

Abstract

BACKGROUND

Patterns of death after trauma are changing due to advances in critical care. We examined mortality in critically injured patients who survived index hospitalization.

METHODS

Retrospective analysis of adults admitted to a Level-1 trauma center (1/1/2000-12/31/2010) with critical injury was conducted comparing patient characteristics, injury, and resource utilization between those who died during follow-up and survivors.

RESULTS

Of 1,695 critically injured patients, 1,135 (67.0%) were discharged alive. As of 5/1/2012, 977/1,135 (86.0%) remained alive; 75/158 (47.5%) patients who died during follow-up, died in the first year. Patients who died had longer hospital stays (24 vs. 17 days) and ICU LOS (17 vs. 8 days), were more likely to undergo tracheostomies (36% vs. 16%) and gastrostomies (39% vs. 16%) and to be discharged to rehabilitation (76% vs. 63%) or skilled nursing (13% vs. 5.8%) facilities than survivors. In multivariable models, male sex, older age, and longer ICU LOS predicted mortality. Patients with ICU LOS >16 days had 1.66 odds of 1-year mortality vs. those with shorter ICU stays.

CONCLUSIONS

ICU LOS during index hospitalization is associated with post-discharge mortality. Patients with prolonged ICU stays after surviving critical injury may benefit from detailed discussions about goals of care after discharge.

摘要

背景

由于重症监护技术的进步,创伤后的死亡模式正在发生变化。我们研究了在首次住院后存活的重症创伤患者的死亡率。

方法

对2000年1月1日至2010年12月31日入住一级创伤中心的成年重症创伤患者进行回顾性分析,比较随访期间死亡患者和存活患者的特征、损伤情况及资源利用情况。

结果

1695例重症创伤患者中,1135例(67.0%)存活出院。截至2012年5月1日,1135例中有977例(86.0%)仍存活;随访期间死亡的75/158例(47.5%)患者在第一年死亡。死亡患者的住院时间(24天对17天)和重症监护病房住院时间(17天对8天)更长,更有可能接受气管切开术(36%对16%)和胃造口术(39%对16%),出院后更有可能被送往康复机构(76%对63%)或专业护理机构(13%对5.8%)。在多变量模型中,男性、年龄较大和重症监护病房住院时间较长可预测死亡率。重症监护病房住院时间>16天的患者1年死亡率是住院时间较短患者的1.66倍。

结论

首次住院期间的重症监护病房住院时间与出院后死亡率相关。重症创伤存活后重症监护病房住院时间延长的患者可能受益于出院后关于护理目标的详细讨论。

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