一名弥漫性皮肤孢子丝菌病患者出现蕈样肉芽肿样损害。
Mycosis fungoides-like lesions in a patient with diffuse cutaneous sporotrichosis.
作者信息
Cotino Sánchez Adriana, Torres-Alvarez Bertha, Gurrola Morales Teodoro, Méndez Martínez Silvia, Saucedo Gárate Mauricio, Castanedo-Cazares Juan Pablo
机构信息
Department of Pathology, Hospital General de Durango, Universidad Juárez del Estado de Durango, Durango, Mexico.
Department of Dermatology, Hospital Central Dr. Ignacio Morones Prieto, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico.
出版信息
Rev Iberoam Micol. 2015 Jul-Sep;32(3):200-3. doi: 10.1016/j.riam.2014.06.009. Epub 2014 Nov 25.
BACKGROUND
Sporotrichosis is a subacute or chronic mycosis acquired by traumatic inoculation or inhalation of fungal conidia. It is caused by the dimorphic fungus Sporothrix, which causes different clinical presentations, being the cutaneous and lymphocutaneous variants being the most frequent. The disseminated cutaneous form is a rare presentation occurring in a minority of cases in Mexico.
CASE REPORT
We report an atypical case of disseminated sporotrichosis in an alcoholic and iatrogenically immunosuppressed patient, whose clinical lesions resembled tumoral-stage mycosis fungoides. Histological examination and culture revealed the presence of Sporothrix schenckii.
CONCLUSIONS
The patient was treated with itraconazole 200mg per day for 4 months with clinical resolution. To the best of our knowledge, this is the first report of this type of clinical manifestation.
背景
孢子丝菌病是一种通过创伤接种或吸入真菌分生孢子而获得的亚急性或慢性真菌病。它由双相真菌申克孢子丝菌引起，可导致不同的临床表现，其中皮肤型和淋巴皮肤型最为常见。播散性皮肤型是一种罕见的表现形式，在墨西哥少数病例中出现。
病例报告
我们报告了一例酒精性和医源性免疫抑制患者的非典型播散性孢子丝菌病病例，其临床病变类似于肿瘤期蕈样肉芽肿。组织学检查和培养显示存在申克孢子丝菌。
结论
患者接受每天200毫克伊曲康唑治疗4个月，临床症状得到缓解。据我们所知，这是此类临床表现的首例报告。
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