Izumo Wataru, Ota Masaho, Narumiya Kosuke, Shirai Yushi, Kudo Kenji, Yamamoto Masakazu
Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666 Japan.
Esophagus. 2015;12(1):91-94. doi: 10.1007/s10388-013-0411-7. Epub 2014 Jan 8.
The patient was a 65-year-old man, who had undergone right nephrectomy for renal cancer in 2002. At that time, histopathological examination revealed clear cell carcinoma (pT3a, pN0, M0, and pStage III). Postoperatively, he received natural interferon alpha (6 million units 3 times a week) from November 2002 to February 2005, and showed no evidence of recurrence. However, he noticed dysphagia in March 2012. Endoscopy revealed a pedunculated polypoid tumor in the mid-esophagus and biopsies were taken showing a clear cell carcinoma. Contrast-enhanced thoracoabdominal CT scanning identified a pedunculated polypoid tumor in the mid-thoracic esophagus and enlargement of a lymph node adjacent to the right main bronchus. With a diagnosis of esophageal and lymph node metastases of renal cancer, the patient underwent esophagectomy with right thoracotomy with reconstruction by a posterior mediastinal stomach tube. Postoperative histopathological examination revealed clear cell carcinoma. Because esophageal metastasis of renal cancer is extremely rare, this case is reported here together with discussions of the relevant literature.
该患者为65岁男性，2002年因肾癌接受了右肾切除术。当时，组织病理学检查显示为透明细胞癌（pT3a，pN0，M0，pⅢ期）。术后，他从2002年11月至2005年2月接受了天然α干扰素（每周3次，每次600万单位）治疗，未出现复发迹象。然而，他在2012年3月出现吞咽困难。内镜检查发现食管中段有一个带蒂的息肉样肿瘤，并进行活检，结果显示为透明细胞癌。增强胸部和腹部CT扫描发现胸段食管中段有一个带蒂的息肉样肿瘤，右主支气管旁的一个淋巴结肿大。诊断为肾癌食管及淋巴结转移后，患者接受了右胸开胸食管切除术，并采用后纵隔胃管重建。术后组织病理学检查显示为透明细胞癌。由于肾癌食管转移极为罕见，现将此病例报告并结合相关文献进行讨论。
