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在糖尿病患者中,护理流程与健康相关生活质量之间没有一致的关联:缺失的环节?

No consistent association between processes-of-care and health-related quality of life among patients with diabetes: a missing link?

机构信息

Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital , Lausanne, Vaud , Switzerland.

出版信息

BMJ Open Diabetes Res Care. 2015 Jan 10;3(1):e000042. doi: 10.1136/bmjdrc-2014-000042. eCollection 2015.

Abstract

PURPOSE

Health-related quality of life (HRQoL) is considered a representative outcome in the evaluation of chronic disease management initiatives emphasizing patient-centered care. We evaluated the association between receipt of processes-of-care (PoC) for diabetes and HRQoL.

METHODS

This cross-sectional study used self-reported data from non-institutionalized adults with diabetes in a Swiss canton. Outcomes were the physical/mental composites of the short form health survey 12 (SF-12) physical composite score, mental composite score (PCS, MCS) and the Audit of Diabetes-Dependent Quality of Life (ADDQoL). Main exposure variables were receipt of six PoC for diabetes in the past 12 months, and the Patient Assessment of Chronic Illness Care (PACIC) score. We performed linear regressions to examine the association between PoC, PACIC and the three composites of HRQoL.

RESULTS

Mean age of the 519 patients was 64.5 years (SD 11.3); 60% were male, 87% reported type 2 or undetermined diabetes and 48% had diabetes for over 10 years. Mean HRQoL scores were SF-12 PCS: 43.4 (SD 10.5), SF-12 MCS: 47.0 (SD 11.2) and ADDQoL: -1.6 (SD 1.6). In adjusted models including all six PoC simultaneously, receipt of influenza vaccine was associated with lower ADDQoL (β=-0.4, p≤0.01) and foot examination was negatively associated with SF-12 PCS (β=-1.8, p≤0.05). There was no association or trend towards a negative association when these PoC were reported as combined measures. PACIC score was associated only with the SF-12 MCS (β=1.6, p≤0.05).

CONCLUSIONS

PoC for diabetes did not show a consistent association with HRQoL in a cross-sectional analysis. This may represent an effect lag time between time of process received and health-related quality of life. Further research is needed to study this complex phenomenon.

摘要

目的

健康相关生活质量(HRQoL)被认为是评估强调以患者为中心的慢性病管理计划的代表性结果。我们评估了接受糖尿病护理流程(PoC)与 HRQoL 之间的关联。

方法

这项横断面研究使用了瑞士一个州非住院成年糖尿病患者的自我报告数据。结果是短格式健康调查 12 项(SF-12)生理综合评分、心理综合评分(PCS、MCS)和糖尿病依赖生活质量评估(ADDQoL)的生理/心理综合评分。主要暴露变量是过去 12 个月内接受 6 项糖尿病 PoC 情况,以及慢性病患者评估护理(PACIC)评分。我们进行了线性回归分析,以检查 PoC、PACIC 与 3 项 HRQoL 综合评分之间的关系。

结果

519 名患者的平均年龄为 64.5 岁(标准差 11.3);60%为男性,87%报告为 2 型或未确定型糖尿病,48%患有糖尿病超过 10 年。平均 HRQoL 评分分别为 SF-12 PCS:43.4(标准差 10.5)、SF-12 MCS:47.0(标准差 11.2)和 ADDQoL:-1.6(标准差 1.6)。在同时纳入所有 6 项 PoC 的调整模型中,接种流感疫苗与 ADDQoL 降低相关(β=-0.4,p≤0.01),足部检查与 SF-12 PCS 呈负相关(β=-1.8,p≤0.05)。当这些 PoC 作为综合措施报告时,没有关联或呈负相关的趋势。PACIC 评分仅与 SF-12 MCS 相关(β=1.6,p≤0.05)。

结论

在横断面分析中,糖尿病的护理流程与 HRQoL 没有一致的关联。这可能代表了接受治疗时间和健康相关生活质量之间的滞后时间效应。需要进一步研究来研究这一复杂现象。

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