Burkhouse Katie L, Woody Mary L, Owens Max, McGeary John E, Knopik Valerie S, Gibb Brandon E
a Department of Psychology , Binghamton University (SUNY) , Binghamton , NY , USA.
b Providence Veterans Affairs Medical Center , Brown University , Providence , RI , USA.
Cogn Emot. 2016;30(2):275-87. doi: 10.1080/02699931.2014.996531. Epub 2015 Jan 26.
The current study examined sensitivity in detecting emotional faces among children of depressed and non-depressed mothers. A second goal was to examine the potential moderating role of the oxytocin receptor gene (OXTR rs53576), which has been linked to emotion recognition in the past. Participants included 247 children (ages 8-14). Children completed a forced choice emotion identification task. Maternal history of major depressive disorder during children's lives was associated with children's sensitivity in detecting emotional faces among children homozygous for the OXTR rs53576 G allele, but not among carriers of the A allele. Among G homozygotes, children of depressed mothers exhibited increased sensitivity in detecting sad faces, and reduced sensitivity in detecting happiness, compared to children of non-depressed mothers.
当前的研究考察了患有抑郁症和未患抑郁症母亲的孩子在识别情绪面孔方面的敏感性。第二个目标是检验过去已与情绪识别相关联的催产素受体基因（OXTR rs53576）的潜在调节作用。参与者包括247名儿童（年龄在8至14岁之间）。孩子们完成了一项强制选择情绪识别任务。在OXTR rs53576 G等位基因纯合子的儿童中，母亲在孩子成长过程中患重度抑郁症的病史与孩子识别情绪面孔的敏感性有关，但在A等位基因携带者中则不然。在G纯合子中，与未患抑郁症母亲的孩子相比，患抑郁症母亲的孩子在识别悲伤面孔时表现出更高的敏感性，而在识别快乐面孔时敏感性降低。
