Mitkovic Voncina Marija, Pejovic Milovancevic Milica, Mandic Maravic Vanja, Lecic Tosevski Dusica
Institute of Mental Health, Palmoticeva 37, Belgrade, 11000, Serbia.
Belgrade University, Faculty of Medicine, Belgrade, Serbia.
Curr Psychiatry Rep. 2017 Aug;19(8):50. doi: 10.1007/s11920-017-0805-7.
Still obscure mechanisms of intergenerational child maltreatment (ITCM) have been investigated partially, from various psychological and biological perspectives and from various time perspectives. This review is aimed at integrating the findings on different temporal ITCM pathways, emphasizing the mind-brain-body interplay.
Psychological mediators of ITCM involve attachment, mentalization, dissociation, social information processing, personality traits, and psychiatric disorders. Neurobiological findings mostly refer to the neural correlates of caregiving and attachment behaviors, affected by several physiological systems (stress-response, immune, oxytocin), which also affect physical health. The latest research clusters around the epigenetic pathways of ITCM, suggesting the additional, prenatal, and preconception forms of transmission. Data suggest that ITCM needs to be conceptualized as a longitudinal process, with various interrelated psychological, neurodevelopmental, and somatic paths. Future research and prevention should take into account both, each path and each phase of ITCM, in an integrative way.
代际儿童虐待（ITCM）的机制仍不明确，已从各种心理和生物学角度以及不同的时间角度进行了部分研究。本综述旨在整合不同时间ITCM途径的研究结果，强调心-脑-身的相互作用。
ITCM的心理中介因素包括依恋、心理化、解离、社会信息处理、人格特质和精神障碍。神经生物学研究结果大多涉及受多种生理系统（应激反应、免疫、催产素）影响的养育和依恋行为的神经关联，这些生理系统也会影响身体健康。最新研究集中在ITCM的表观遗传途径，提示了额外的、产前和孕前的传播形式。数据表明，ITCM需要被概念化为一个纵向过程，具有各种相互关联的心理、神经发育和躯体途径。未来的研究和预防应综合考虑ITCM的每条途径和每个阶段。
