Department of Child and Adolescent Psychiatry, Karol Jonscher Clinical Hospital, Poznan University of Medical Sciences, Szpitalna St. 27/33, 60-572 Poznan, Poland.
Department of Psychiatric Genetics, Medical Biology Center, Poznan University of Medical Sciences, Rokietnicka St. 8, 60-806 Poznan, Poland.
Int J Mol Sci. 2024 Nov 9;25(22):12046. doi: 10.3390/ijms252212046.
Borderline personality disorder constitutes a significant medical challenge. Despite the fact that its occurrence among adolescents is currently attracting increasing interest from both clinicians and researchers, there is still insufficient data on this phenomenon. The etiology and maintenance of borderline personality disorder are not yet fully comprehended. Neuropeptides, including oxytocin and vasopressin, are considered to be involved in the development of this condition. The mechanism behind the actions of these neurohormones requires further investigation. Our work aims to collect and analyze the available research and existing hypotheses on the role of oxytocin and vasopressin in people with borderline personality disorder, with special attention drawn to adolescents suffering from this condition.
边缘型人格障碍是一个重大的医学挑战。尽管目前临床医生和研究人员对青少年群体中出现的边缘型人格障碍越来越感兴趣，但对于这一现象仍缺乏足够的数据。边缘型人格障碍的病因和维持机制尚未完全被理解。神经肽，包括催产素和加压素，被认为与这种情况的发展有关。这些神经激素作用的机制需要进一步研究。我们的工作旨在收集和分析现有的关于催产素和加压素在边缘型人格障碍患者中的作用的研究和现有假说，特别关注患有这种疾病的青少年。
