[Application of CaO-P2O5-MgO-SiO2-CaF system glass ceramics to periodontal therapy. Histopathological observation after implantation in furcation bony defect in monkeys].

This study was carried out in order to determine the efficacy of CaO-P2O5-MgO-SiO2-CaF system glass ceramics, which are made as implant materials, for treatment of furcation lesions. Glass ceramic granules were implanted in artificial class II furcation bony defects in monkeys. As controls, non-implanted sites were preserved. Radiographic and various clinical examinations were performed before surgery and at 0, 2, 4 and 8 weeks after implantation. Two, 4 and 8 weeks after implantation, two monkeys were sacrificed and the mandibles were sectioned for histopathological observation. The results obtained were as follows; 1. During the experiment, no clinical problems or abnormal response at the sites of glass ceramic implantation were observed. 2. In clinical observation, no remarkable differences were obtained between control sites and implanted sites. 3. Two and 4 weeks after surgery, remarkable regeneration of bone was shown in the implanted sites. However 8 weeks after surgery, the difference between implanted and control sites was not so clear.