[Qanadli与Mastora肺栓塞指数在评估骑跨型肺栓塞中的价值比较]

[Comparison of value of Qanadli versus Mastora pulmonary embolism index in evaluating straddle-type pulmonary embolism].

作者信息

Chen Shanshan, Cheng Ruirui, Zhang Guojun

机构信息

First Branch, Department of Respiratory Medicine, First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.

First Branch, Department of Respiratory Medicine, First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China. Email:

出版信息

Zhonghua Yi Xue Za Zhi. 2014 Dec 16;94(46):3629-32.

PMID:25622952

Abstract

OBJECTIVE

To compare the value of Qanadli versus Mastora pulmonary embolism index in evaluating straddle-type pulmonary embolism by computed tomography (CT).

METHODS

The clinical data were collected for 38 hospitalized patients with straddle-type pulmonary embolism diagnosed by CT pulmonary angiography (CTPA) from January 2011 to May 2014. There were 20 males and 18 females with an average age of (59.2 ± 17.4 years). And the serum levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) and D-dimer were recorded. And Qanadli and Mastora pulmonary embolism indices were used to independently determine the CT embolism indices. Difference and correlation between Quandli and Mastora pulmonary embolism index were analyzed. And the relations between Qanadli score, Mastora score and serum parameters and right heart function parameters were analyzed.

RESULTS

Qanadli score of 38 patients was 20.0 ± 0.0 while Mastora score 80.9 ± 26.1. No significant correlation existed between Qanadli and Mastora scores. Median serum D-dimer level was 708.5 (9.6, 1 025.5) µg/L and median NT-proBNP 1 358.5 (576.7, 3 047.3) ng/L. Qanadli score was not statistically significantly correlated with serum D-dimer or NT-proBNP level. Mastora score was not correlated with serum D-dimer level statistically significantly, but it was positively correlated with the level of NT-proBNP (r = 0.495, P = 0.010). No significant correlation existed between Qanadli score and right atrial diameter, right ventricular/left ventricular diameter ratio on CTPA. Mastora score was positively correlated with right atrial diameter/left atrial diameter ratio (r = 0.627, P < 0.001) and right ventricular diameter/left ventricular diameter ratio on CTPA (r = 0.628, P < 0.001). The Mastora score was not significantly correlated with main pulmonary artery diameter and main pulmonary artery diameter/ascending aorta diameter ratio on CTPA.

CONCLUSIONS

Mastora pulmonary embolism index is better than Qanadli pulmonary embolism index in evaluating straddle-type pulmonary embolism. Correlated with right ventricular function, the former reflects pulmonary embolic load and change of right heart function.

摘要

目的

比较卡纳德利（Qanadli）与马斯特拉（Mastora）肺栓塞指数在通过计算机断层扫描（CT）评估骑跨型肺栓塞中的价值。

方法

收集2011年1月至2014年5月期间38例经CT肺动脉造影（CTPA）诊断为骑跨型肺栓塞的住院患者的临床资料。其中男性20例，女性18例，平均年龄（59.2±17.4岁）。记录血清N末端脑钠肽前体（NT-proBNP）和D-二聚体水平。使用卡纳德利和马斯特拉肺栓塞指数独立确定CT栓塞指数。分析卡纳德利和马斯特拉肺栓塞指数之间的差异和相关性。并分析卡纳德利评分、马斯特拉评分与血清参数及右心功能参数之间的关系。

结果

38例患者的卡纳德利评分为20.0±0.0，而马斯特拉评分为80.9±26.1。卡纳德利评分与马斯特拉评分之间无显著相关性。血清D-二聚体水平中位数为708.5（9.6，1025.5）μg/L，NT-proBNP中位数为1358.5（576.7，3047.3）ng/L。卡纳德利评分与血清D-二聚体或NT-proBNP水平无统计学显著相关性。马斯特拉评分与血清D-二聚体水平无统计学显著相关性，但与NT-proBNP水平呈正相关（r = 0.495，P = 0.010）。卡纳德利评分与CTPA上的右心房直径、右心室/左心室直径比值无显著相关性。马斯特拉评分与CTPA上的右心房直径/左心房直径比值（r = 0.627，P < 0.001）和右心室直径/左心室直径比值呈正相关（r = 0.628，P < 0.001）。马斯特拉评分与CTPA上的主肺动脉直径及主肺动脉直径/升主动脉直径比值无显著相关性。