Tamrat Lemlem, Gessesse Girum W, Gelaw Yeshigeta
Department of Ophthalmology, St. Paul Millennium Medical College, Addis Ababa, Ethiopia.
Department of Ophthalmology, Jimma University, Jimma, Ethiopia.
Middle East Afr J Ophthalmol. 2015 Jan-Mar;22(1):59-63. doi: 10.4103/0974-9233.148350.
Successful outcomes of medical treatment for glaucoma require proper and daily use of medication to prevent disease progression. The aim of this study was to determine the adherence to anti-glaucoma medications and factors associated with non-adherence among patients with ocular hypertension (OHT) or glaucoma at Jimma University Specialized Hospital, Ethiopia.
A hospital based cross sectional study was conducted on 200 consecutive patients from July to November 2010 at Jimma University Hospital in Southwest Ethiopia. Patients with OHT or glaucoma who were taking topical anti-glaucoma medications for more than six months were included. The study subjects were interviewed and their medical records were reviewed. Non-adherence to glaucoma therapy (NAGT) was defined as self-reported on missed medications or missed appointments, or a physician noting poor adherence. A P < 0.05 was statistically significant.
Overall, 135 (67.5%) patients were non adherent to glaucoma therapy. Non adherence was associated with older age (P = 0.04), advanced stage of glaucoma (P = 0.01), longer frequency of follow up (P = 0.00) and financial problem (P = 0.000). Sex (P = 0.53), level of education (P = 0.09), and marital status (P = 0.77) were not statistically significantly associated with non-adherence to anti-glaucoma drug treatment.
A relatively high proportion of patients were not adhering to the medications regimen for glaucoma. Older age, advanced glaucoma, lengthier frequency of follow-up and financial hardship were associated with non-adherence. Eye care providers should be aware of the problem of non-adherence to topical medications.
青光眼的药物治疗要取得成功,需要正确且每日使用药物以防止疾病进展。本研究的目的是确定埃塞俄比亚吉马大学专科医院高眼压症(OHT)或青光眼患者对抗青光眼药物的依从性以及与不依从相关的因素。
2010年7月至11月在埃塞俄比亚西南部的吉马大学医院对200例连续患者进行了一项基于医院的横断面研究。纳入了使用局部抗青光眼药物超过6个月的高眼压症或青光眼患者。对研究对象进行了访谈并查阅了他们的病历。青光眼治疗不依从(NAGT)定义为自我报告的漏服药物或错过预约,或医生指出依从性差。P < 0.05具有统计学意义。
总体而言,135例(67.5%)患者青光眼治疗不依从。不依从与年龄较大(P = 0.04)、青光眼晚期(P = 0.01)、随访频率较高(P = 0.00)和经济问题(P = 0.000)相关。性别(P = 0.53)、教育程度(P = 0.09)和婚姻状况(P = 0.77)与抗青光眼药物治疗不依从无统计学显著相关性。
相当一部分患者未遵守青光眼药物治疗方案。年龄较大、青光眼晚期、随访频率较长和经济困难与不依从相关。眼科护理人员应意识到局部用药不依从的问题。