栓塞术在脑动静脉畸形治疗中的作用。
Role of embolization for cerebral arteriovenous malformations.
作者信息
Ellis Jason A, Lavine Sean D
机构信息
Columbia University Medical Center, New York, New York.
出版信息
Methodist Debakey Cardiovasc J. 2014 Oct-Dec;10(4):234-9. doi: 10.14797/mdcj-10-4-234.
Abstract
Cerebral arteriovenous malformations (AVMs) are complex high-flow lesions that can result in devastating neurological injury when they hemorrhage. Embolization is a critical component in the management of many patients with cerebral AVMs. Embolization may be used as an independent curative therapy or more commonly in an adjuvant fashion prior to either micro- or radiosurgery. Although the treatment-related morbidity and mortality for AVMs--including that due to microsurgery, embolization, and radiosurgery--can be substantial, its natural history offers little solace. Fortunately, care by a multidisciplinary team experienced in the comprehensive management of AVMs can offer excellent results in most cases.
摘要
脑动静脉畸形（AVM）是复杂的高流量病变，出血时可导致毁灭性的神经损伤。栓塞是许多脑AVM患者治疗的关键组成部分。栓塞可作为独立的根治性治疗方法，或更常见的是在显微手术或放射外科手术之前作为辅助治疗方法。尽管AVM的治疗相关发病率和死亡率——包括显微手术、栓塞和放射外科手术导致的发病率和死亡率——可能很高，但其自然病程却不容乐观。幸运的是，由经验丰富的多学科团队对AVM进行综合管理，在大多数情况下都能取得良好的效果。
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