Department of Gastroenterology, Sheffield Teaching Hospitals, Sheffield, United Kingdom.
Department of Gastroenterology, University Hospital, Southampton, United Kingdom.
Endoscopy. 2015 Jul;47(7):650-3. doi: 10.1055/s-0034-1391329. Epub 2015 Jan 27.
Capsule endoscopy is well tolerated but control of its movement is needed in order to visualize the whole gastric surface. Technological developments have produced an external magnet to allow manipulation of the capsule within the gastric cavity. The aim of this study was to compare magnetically steerable gastric capsule endoscopy (MSGCE) with flexible endoscopy for the detection of beads in a porcine stomach.
Beads were sewn onto the mucosal surface of 12 ex vivo porcine stomachs. Each model was examined by flexible endoscopy and MSGCE by two blinded investigators. MSGCE was performed according to a protocol using positional changes and magnetic steering. Outcome measures were number and location of beads identified, and duration of procedure.
Flexible endoscopy identified 79 /90 beads (88 %), and MSGCE identified 80 /90 (89 %). The difference in sensitivities was 1.11 (95 % confidence interval 0.06 - 28.26). Thus, MSGCE was noninferior to flexible endoscopy. Mean examination times for flexible endoscopy and MSGCE were 3.34 minutes and 9.90 minutes, respectively.
MSGCE was equivalent to conventional flexible endoscopy in the detection of beads in a porcine stomach model.
胶囊内镜检查耐受性良好，但为了观察整个胃表面，需要控制胶囊的运动。技术的发展产生了外部磁铁，以允许在胃腔内操纵胶囊。本研究的目的是比较磁引导胃胶囊内镜（MSGCE）与软式内镜检查在猪胃中检测珠子的效果。
将珠子缝制到 12 个离体猪胃的黏膜表面。每个模型均由两名盲法观察者进行软式内镜和 MSGCE 检查。根据使用位置变化和磁引导的方案进行 MSGCE 检查。主要评估指标为识别的珠子数量和位置，以及操作时间。
软式内镜检查共识别 79/90 个珠子（88%），而 MSGCE 识别 80/90 个珠子（89%）。灵敏度的差异为 1.11（95%置信区间 0.06-28.26）。因此，MSGCE 与软式内镜检查相当。软式内镜检查和 MSGCE 的平均检查时间分别为 3.34 分钟和 9.90 分钟。
在猪胃模型中，MSGCE 在检测珠子方面与传统软式内镜检查相当。
