萨尔瓦多15个短串联重复序列（STR）位点的基因多态性
Genetic polymorphism of 15 STR loci in El Salvador.
作者信息
Muñoz Pablo, Pinto de Erazo Eugenia Leticia, Baeza Carlos, Arroyo-Pardo Eduardo, López-Parra Ana Maria
机构信息
Laboratory of Forensic Genetics and Population Genetics, Department of Toxicology and Health Sanitary, Faculty of Medicine, Complutense University of Madrid, Madrid, Spain.
出版信息
Int J Legal Med. 2015 Sep;129(5):991-3. doi: 10.1007/s00414-015-1148-8. Epub 2015 Jan 28.
The aim of this study was to estimate the allelic frequencies of the 15 short tandem repeat (STR) loci included in AmpFlSTRIdentifiler PCR Amplification Kit. Biological samples were obtained from 109 unrelated individuals from El Salvador. Allelic frequencies and forensic parameters were calculated. All loci showed no departure from Hardy-Weinberg equilibrium after Bonferroni correction. The obtained frequencies were compared with other previously reported population data. The multidimensional scaling plot and the neighbor-joining phylogeny supported a high native Mesoamerican contribution.
本研究的目的是估计AmpFlSTR Identifiler PCR扩增试剂盒中包含的15个短串联重复序列（STR）位点的等位基因频率。生物样本取自萨尔瓦多109名无亲缘关系的个体。计算了等位基因频率和法医学参数。经Bonferroni校正后，所有位点均未偏离哈迪-温伯格平衡。将获得的频率与其他先前报道的人群数据进行了比较。多维标度图和邻接法系统发育分析支持了中美洲本土的高贡献度。
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