Gołabek W, Orzelski L, Siwiec H
Ann Univ Mariae Curie Sklodowska Med. 1989;44:53-7.
A decrease in serum iron and total iron binding capacity (TIBC) has been seen in patients with various malignancies. Similar iron level and TIBC alterations we have found in patients with larynx cancer. Estimation of TIBC reflects the quantity of transferrin which is the iron carrier in serum. The serum iron and transferrin changes cannot be used for diagnostic purposes because they are not specific to malignancies. Such alterations have been also seen in inflammatory and infectious diseases, heart infarct and anaemias. However, it is of interest whether elimination of neoplastic tissue from an organism brings back the decreased serum iron and TIBC to normal values.
在患有各种恶性肿瘤的患者中，已观察到血清铁和总铁结合力（TIBC）降低。我们在喉癌患者中也发现了类似的铁水平和TIBC改变。TIBC的测定反映了转铁蛋白的量，转铁蛋白是血清中的铁载体。血清铁和转铁蛋白的变化不能用于诊断目的，因为它们并非恶性肿瘤所特有。在炎症和感染性疾病、心肌梗死及贫血中也可见到此类变化。然而，机体中肿瘤组织的清除是否会使降低的血清铁和TIBC恢复到正常水平，这一点很值得关注。
