Singhal U, Mohsin S, Saini K, Singhal K C
Department of Physiology, J.N. Medical College, Aligarh Muslim University.
Indian J Physiol Pharmacol. 1993 Jan;37(1):71-4.
Serum levels of iron and transferrin, and percent saturation of total iron binding capacity (TIBC) and latent iron binding capacity were estimated in 89 women in their I, II and IIIrd trimester of pregnancy. Associated infective, metabolic or degenerative diseases were excluded after clinical examination. The women were divided into three groups of normal, mildly anaemic and severely anaemic. In the normal group serum iron levels were within normal range irrespective of period of gestation, whereas in the anaemic groups, these were lower. Serum transferrin levels were significantly low in II and III trimester of pregnancy of anaemic women. Percent saturation of TIBC was even lower than normal in Ist trimester of pregnancy in normal pregnancy (27.12%). However in mild anaemic there was significant fall and in severe anaemia, it was very low, leaving a vast latent iron binding capacity. The decrease of % saturation of TIBC even in normal pregnant women is indicative of inherent poor stores, which may be due to defective diet.
对89名处于妊娠Ⅰ、Ⅱ、Ⅲ期的女性进行了血清铁、转铁蛋白水平以及总铁结合力（TIBC）百分饱和度和潜在铁结合力的评估。临床检查后排除了相关的感染性、代谢性或退行性疾病。这些女性被分为正常、轻度贫血和重度贫血三组。正常组血清铁水平在整个妊娠期均处于正常范围，而贫血组的血清铁水平较低。贫血女性在妊娠Ⅱ期和Ⅲ期血清转铁蛋白水平显著降低。正常妊娠时，TIBC百分饱和度在妊娠Ⅰ期甚至低于正常水平（27.12%）。然而，轻度贫血时显著下降，重度贫血时则非常低，存在大量潜在铁结合力。即使是正常孕妇，TIBC百分饱和度的降低也表明体内储存不足，这可能是由于饮食不良所致。
