• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

有或无控制性低血压麻醉的颌面病例术中失血、术野质量及手术时长的对比研究

Comparative Study of Blood Loss, Quality of Surgical Field and Duration of Surgery in Maxillofacial Cases with and without Hypotensive Anesthesia.

作者信息

Prasant M C, Kar Sanjay, Rastogi Saurabh, Hada Pratiksha, Ali Fareedi Mukram, Mudhol Anupama

机构信息

Dean & Head, Department of Oral & Maxillofacial Surgery, RKDF Dental College, Bhopal, Madhya Pradesh, India.

Professor, Department of Oral & Maxillofacial Surgery, Mansarovar Dental College, Hospital & Research Centre, Bhopal, Madhya Pradesh, India.

出版信息

J Int Oral Health. 2014 Nov-Dec;6(6):18-21.

PMID:25628477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4295448/
Abstract

BACKGROUND

Oral and maxillofacial surgeons are concern about the intraoperative bleeding because blood supply to face is very generous. Increased blood loss may lead to the need for transfusion of blood and blood products and hence patients are exposed to the risks associated with it. Hence, this study was undertaken to compare whether there is any significant difference in blood loss, surgical field and duration of surgery in patients undergoing maxillofacial surgeries with and without hypotensive anesthesia.

MATERIALS AND METHODS

The study was conducted on patients undergoing various maxillofacial surgeries. The patients were randomly divided into two groups, the study group and the control group. In the study group patients, induced hypotension was used in order to maintain systolic pressure of 80-90 mm Hg. In the control group patients, normotensive anesthesia was used. Estimation of blood loss (EBS), quality of the surgical field and duration of surgery was calculated for both groups in three types of surgical procedures. Statistical analysis was performed by using two-tailed Pearson correlation test.

RESULTS

EBS was found to be significantly less in all the surgical procedures carried out under hypotensive anesthesia (P < 0.05). The quality of the surgical field was better in cases with induced hypotension, but there was no significant difference in duration of the procedures with and without induced hypotension.

CONCLUSION

Our study shows that hypotensive anesthesia can be safely used in almost all maxillofacial surgical procedures with reduced blood loss and improved surgical field.

摘要

背景

口腔颌面外科医生关注术中出血情况,因为面部血供非常丰富。失血增加可能导致需要输血及血液制品,从而使患者面临与之相关的风险。因此,本研究旨在比较在接受颌面部手术的患者中,采用与未采用控制性低血压麻醉时,在失血量、手术视野和手术时长方面是否存在显著差异。

材料与方法

本研究针对接受各类颌面部手术的患者开展。患者被随机分为两组,即研究组和对照组。研究组患者采用控制性低血压以维持收缩压在80 - 90 mmHg。对照组患者采用正常血压麻醉。针对两组患者在三种手术术式中分别计算失血量估计值(EBS)、手术视野质量和手术时长。采用双尾Pearson相关性检验进行统计分析。

结果

发现在控制性低血压麻醉下进行的所有手术中,失血量估计值均显著更低(P < 0.05)。控制性低血压病例的手术视野质量更佳,但有无控制性低血压情况下手术时长无显著差异。

结论

我们的研究表明,控制性低血压麻醉几乎可安全用于所有颌面部外科手术,能减少失血量并改善手术视野。

相似文献

1
Comparative Study of Blood Loss, Quality of Surgical Field and Duration of Surgery in Maxillofacial Cases with and without Hypotensive Anesthesia.有或无控制性低血压麻醉的颌面病例术中失血、术野质量及手术时长的对比研究
J Int Oral Health. 2014 Nov-Dec;6(6):18-21.
2
Effect of Induced Hypotensive Anesthesia and Normotensive Anesthesia on Intraoperative Blood Loss During Orthognathic Surgery: A Systematic Review.控制性低血压麻醉和正常血压麻醉对正颌手术术中失血的影响:一项系统评价
J Maxillofac Oral Surg. 2024 Oct;23(5):1127-1137. doi: 10.1007/s12663-023-02034-y. Epub 2023 Nov 13.
3
Comparative Evaluation of Hypotensive and Normotensive Anesthesia on LeFort I Osteotomies: A Randomized, Double-Blind, Prospective Clinical Study.低血压麻醉与正常血压麻醉用于LeFort I型截骨术的比较评估:一项随机、双盲、前瞻性临床研究。
J Maxillofac Oral Surg. 2020 Jun;19(2):240-245. doi: 10.1007/s12663-019-01325-7. Epub 2020 Jan 17.
4
Effects of Hypotensive Anesthesia on Reducing Intraoperative Blood Loss, Duration of Operation, and Quality of Surgical Field During Orthognathic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.控制性低血压麻醉对正颌手术中减少术中失血、手术时间及术野质量的影响:一项随机对照试验的系统评价和Meta分析
J Oral Maxillofac Surg. 2017 Jan;75(1):73-86. doi: 10.1016/j.joms.2016.07.012. Epub 2016 Jul 25.
5
Hypotensive anesthesia versus normotensive anesthesia during major maxillofacial surgery: a review of the literature.颌面外科大手术中低血压麻醉与正常血压麻醉:文献综述
ScientificWorldJournal. 2015;2015:480728. doi: 10.1155/2015/480728. Epub 2015 Feb 23.
6
Effect of induced hypotensive anaesthesia vs isovolaemic haemodilution on blood loss and transfusion requirements in orthognathic surgery: a prospective, single-blinded, randomized, controlled clinical study.控制性降压麻醉与等容血液稀释对正颌手术患者失血量和输血需求的影响:一项前瞻性、单盲、随机、对照临床研究。
Int J Oral Maxillofac Surg. 2010 Dec;39(12):1168-74. doi: 10.1016/j.ijom.2010.09.003. Epub 2010 Oct 18.
7
Hypotensive Epidural Anesthesia Reduces Blood Loss in Pelvic and Sacral Bone Tumor Resections.低血压硬膜外麻醉可减少骨盆和骶骨肿瘤切除术中的失血量。
Clin Orthop Relat Res. 2017 Mar;475(3):634-640. doi: 10.1007/s11999-016-4858-4. Epub 2016 May 12.
8
Influence of hypotensive and normotensive anesthesia on platelet aggregability and hemostatic markers in orthognathic surgery.降压麻醉与正常血压麻醉对正颌外科手术中血小板聚集性及止血标志物的影响。
Thromb Res. 2001 Aug 1;103(3):185-92. doi: 10.1016/s0049-3848(01)00316-4.
9
Induced hypotensive anesthesia for adolescent orthognathic surgery patients.青少年正颌外科手术患者的控制性低血压麻醉
J Oral Maxillofac Surg. 1996 Jun;54(6):680-3; discussion 683-4. doi: 10.1016/s0278-2391(96)90679-5.
10
Is hypotensive anaesthesia guided by invasive intraarterial monitoring required for orthognathic surgery? - A retrospective review of anaesthetic practice and intraoperative blood loss in orthognathic surgery in a tertiary hospital.正颌手术是否需要有创动脉监测引导的低血压麻醉?——三级医院正颌手术麻醉实践与术中失血的回顾性分析
Indian J Anaesth. 2021 Jul;65(7):525-532. doi: 10.4103/ija.IJA_201_21. Epub 2021 Jul 23.

引用本文的文献

1
Hypotensive anesthesia in maxillofacial surgeries: Current concepts.颌面外科手术中的低血压麻醉:当前概念
Natl J Maxillofac Surg. 2025 May-Aug;16(2):212-219. doi: 10.4103/njms.njms_129_24. Epub 2025 Aug 30.
2
A Single-Stage Surgery of Mandibular Angle Ostectomy and Corticectomy Combined with Masseter Muscle Resection for Facial Contouring in the Vietnamese Population.越南人群下颌角截骨术、皮质骨切除术联合咬肌切除术的单阶段面部轮廓整形手术
Aesthetic Plast Surg. 2025 Sep 16. doi: 10.1007/s00266-025-05244-6.
3
Is Blood Transfusion Justified During Soft Tissue Surgery in Noma Patients? A One-Year Appraisal at Noma Children Hospital, Sokoto, Nigeria.在走马疳患者的软组织手术中输血是否合理?尼日利亚索科托走马疳儿童医院的一年评估。
J West Afr Coll Surg. 2022 Apr-Jun;12(2):1-6. doi: 10.4103/jwas.jwas_55_22. Epub 2022 Aug 27.
4
Estimation of Blood Loss in Oral and Maxillofacial Surgery by Measurements of Low Haemoglobin Levels in Mixtures of Blood, Saliva and Saline: a Laboratory Study.通过测量血液、唾液和盐水混合物中的低血红蛋白水平来估算口腔颌面外科手术中的失血量:一项实验室研究
J Oral Maxillofac Res. 2021 Jun 30;12(2):e3. doi: 10.5037/jomr.2021.12203. eCollection 2021 Apr-Jun.
5
Is hypotensive anaesthesia guided by invasive intraarterial monitoring required for orthognathic surgery? - A retrospective review of anaesthetic practice and intraoperative blood loss in orthognathic surgery in a tertiary hospital.正颌手术是否需要有创动脉监测引导的低血压麻醉?——三级医院正颌手术麻醉实践与术中失血的回顾性分析
Indian J Anaesth. 2021 Jul;65(7):525-532. doi: 10.4103/ija.IJA_201_21. Epub 2021 Jul 23.
6
The Role of Permissive and Induced Hypotension in Current Neuroanesthesia Practice.允许性低血压和诱导性低血压在当前神经麻醉实践中的作用
Front Surg. 2017 Jan 30;4:1. doi: 10.3389/fsurg.2017.00001. eCollection 2017.
7
The effect of dexmedetomidine added to preemptive (2% lignocaine with adrenaline) infiltration on intraoperative hemodynamics and postoperative pain after ambulatory maxillofacial surgeries under general anesthesia.右美托咪定添加至超前(含肾上腺素的2%利多卡因)浸润麻醉对全身麻醉下日间颌面外科手术术中血流动力学及术后疼痛的影响。
Anesth Essays Res. 2016 May-Aug;10(2):324-31. doi: 10.4103/0259-1162.167837.

本文引用的文献

1
Risks and benefits of deliberate hypotension in anaesthesia: a systematic review.麻醉中控制性低血压的风险与益处:一项系统评价
Int J Oral Maxillofac Surg. 2008 Aug;37(8):687-703. doi: 10.1016/j.ijom.2008.03.011. Epub 2008 Jun 3.
2
Controlled hypotension: a guide to drug choice.控制性低血压:药物选择指南
Drugs. 2007;67(7):1053-76. doi: 10.2165/00003495-200767070-00007.
3
Hypotensive anaesthesia and blood loss in orthognathic surgery: a clinical study.正颌外科手术中的低血压麻醉与失血:一项临床研究
Br J Oral Maxillofac Surg. 2001 Apr;39(2):138-40. doi: 10.1054/bjom.2000.0593.
4
Intra-operative blood loss and operating time in orthognathic surgery using induced hypotensive general anaesthesia: prospective study.
Hong Kong Med J. 2000 Sep;6(3):307-11.
5
Multimodal strategy for reduction of homologous transfusions in cranio-maxillofacial surgery.减少颅颌面外科手术中同种异体输血的多模式策略。
Int J Oral Maxillofac Surg. 1999 Apr;28(2):137-42.
6
Induced hypotension may influence blood loss in orthognathic surgery, but it is not crucial.控制性低血压可能会影响正颌外科手术中的失血量,但并非关键因素。
Scand J Plast Reconstr Surg Hand Surg. 1997 Dec;31(4):311-7. doi: 10.3109/02844319709008977.
7
Nicardipine for controlled hypotension during orthognathic surgery.
Plast Reconstr Surg. 1997 May;99(6):1539-43.
8
Induced hypotension during anesthesia with special reference to orthognathic surgery.麻醉期间的控制性低血压,特别涉及正颌外科手术。
Anesth Prog. 1995;42(2):41-58.
9
Induced hypotensive anesthesia for adolescent orthognathic surgery patients.青少年正颌外科手术患者的控制性低血压麻醉
J Oral Maxillofac Surg. 1996 Jun;54(6):680-3; discussion 683-4. doi: 10.1016/s0278-2391(96)90679-5.
10
Blood loss and transfusion requirements in orthognatic surgery.正颌外科手术中的失血与输血需求
J Oral Maxillofac Surg. 1996 Jan;54(1):21-4; discussion 25-6. doi: 10.1016/s0278-2391(96)90295-5.